Literature DB >> 18544956

Long-term aspiration following treatment for head and neck cancer.

Nam P Nguyen1, Candace C Moltz, Cheryl Frank, Paul Vos, Herbert J Smith, Ulf Karlsson, Ly M Nguyen, Sue Rose, Suresh Dutta, Nga Nguyen, Sabah Sallah.   

Abstract

BACKGROUND: Dysphagia and aspiration are long-term complications with life-threatening consequences following treatment of head and neck cancer. We would like to assess the prevalence of aspiration in patients with long-term persistence of dysphagia (1 year or more) following treatment for head and neck cancer and to identify potential risk factors of aspiration.
METHODS: Modified barium swallow (MBS) examinations were performed in cancer-free patients who complained of dysphagia following treatment for head and neck cancer. The severity of the dysphagia was graded on a scale of 1-7.
RESULTS: Between 1992 and 2004, 74 patients with dysphagia underwent MBS 12-152 months following treatment (median 29 months). There were 2 grade 1, 22 grade 3, 21 grade 4, 11 grade 5, 7 grade 6, and 11 grade 7 cases. Twenty-nine patients (39%) had long-term aspiration at a median follow-up of 25 months (range 12-82). Eighteen patients (24%) required permanent gastrostomy because of severe aspiration. Type of treatment and disease stage did not seem to influence long-term aspiration risk.
CONCLUSION: Patients with long-term dysphagia after treatment for head and neck cancer are at risk of aspiration. MBS should be performed to identify these patients. Copyright 2008 S. Karger AG, Basel.

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Year:  2008        PMID: 18544956     DOI: 10.1159/000138976

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  8 in total

Review 1.  Dysphagia in head and neck cancer patients treated with chemoradiotherapy.

Authors:  Nele Platteaux; Piet Dirix; Eddy Dejaeger; Sandra Nuyts
Journal:  Dysphagia       Date:  2009-08-27       Impact factor: 3.438

Review 2.  Effects of chemoradiotherapy on voice and swallowing.

Authors:  Cathy L Lazarus
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2009-06       Impact factor: 2.064

3.  Complications of radiotherapy in laryngopharyngeal cancer: effects of a prospective smoking cessation program.

Authors:  Jose P Zevallos; Michael J Mallen; Cho Y Lam; Maher Karam-Hage; Jan Blalock; David W Wetter; Adam S Garden; Erich M Sturgis; Paul M Cinciripini
Journal:  Cancer       Date:  2009-10-01       Impact factor: 6.921

4.  Effects of exercise on swallowing and tongue strength in patients with oral and oropharyngeal cancer treated with primary radiotherapy with or without chemotherapy.

Authors:  C L Lazarus; H Husaini; D Falciglia; M DeLacure; R C Branski; D Kraus; N Lee; M Ho; C Ganz; B Smith; N Sanfilippo
Journal:  Int J Oral Maxillofac Surg       Date:  2013-12-11       Impact factor: 2.986

5.  Swallowing disorders after treatment for head and neck cancer.

Authors:  Martina Pezdirec; Primoz Strojan; Irena Hocevar Boltezar
Journal:  Radiol Oncol       Date:  2019-06-01       Impact factor: 2.991

6.  Study protocol for a randomized controlled trial: prophylactic swallowing exercises in head-and-neck cancer patients treated with (chemo)radiotherapy (PRESTO trial).

Authors:  Margot Baudelet; Leen Van den Steen; Fréderic Duprez; Marc De Bodt; Sarah Deschuymer; Ann Goeleven; Isabel Hutsebaut; Steven Mariën; Sabine Meersschout; Daan Nevens; Sandra Nuyts; Marc Peeters; Pol Specenier; Michiel Van den Brekel; Lisette van der Molen; Caroline Vandenbruaene; Olivier Vanderveken; Joost Van Dinther; Carl Van Laer; Tom Vauterin; Hilde Verstraete; Gwen Van Nuffelen
Journal:  Trials       Date:  2020-03-02       Impact factor: 2.279

7.  Tracheoesophageal Diversion and Laryngotracheal Separation Procedures for Radiotherapy-Related Intractable Aspiration Pneumonia in Nasopharyngeal Carcinoma.

Authors:  Wei Gu; Jian Wang
Journal:  Biomed Res Int       Date:  2022-07-23       Impact factor: 3.246

8.  Study protocol for a randomized controlled trial: tongue strengthening exercises in head and neck cancer patients, does exercise load matter?

Authors:  Gwen Van Nuffelen; Leen Van den Steen; Olivier Vanderveken; Pol Specenier; Carl Van Laer; Diane Van Rompaey; Cindy Guns; Steven Mariën; Marc Peeters; Paul Van de Heyning; Jan Vanderwegen; Marc De Bodt
Journal:  Trials       Date:  2015-09-04       Impact factor: 2.279

  8 in total

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