Literature DB >> 18544346

Crucial role of peroxiredoxin III in placental antioxidant defense of mice.

Lianqin Li1, Wataru Shoji, Hiroaki Oshima, Masuo Obinata, Manabu Fukumoto, Naoko Kanno.   

Abstract

We observed frequent stillbirth in peroxiredoxin III (PrxIII) knockout maternal mice. Quantitative real time PCR (qRT-PCR) and Western-blot analysis revealed increased oxidative stress in placentas that were deficient in PrxIII. We did not find significant difference between PrxIII knockout maternal mice and wild-type littermates in hematological parameters, fetal number, and embryonic development. Nevertheless, we noticed enhanced expression of PrxI in erythrocytes of pregnant knockout mice. Our results provided in vivo evidence that PrxIII played a crucial role in placental antioxidant defense. Up-regulation of PrxI might provide a compensation that protected erythrocytes against oxidative damage.

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Year:  2008        PMID： 18544346     DOI： 10.1016/j.febslet.2008.05.050

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  21 in total

Review 1.  Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?

Authors:  Jennalynn Styskal; Holly Van Remmen; Arlan Richardson; Adam B Salmon
Journal:  Free Radic Biol Med       Date:  2011-10-20       Impact factor: 7.376

2.  Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila.

Authors:  Svetlana N Radyuk; Igor Rebrin; Vladimir I Klichko; Barbara H Sohal; Katarzyna Michalak; Judith Benes; Rajindar S Sohal; William C Orr
Journal:  Free Radic Biol Med       Date:  2010-10-19       Impact factor: 7.376

3.  The dual-targeted plant sulfiredoxin retroreduces the sulfinic form of atypical mitochondrial peroxiredoxin.

Authors:  Iván Iglesias-Baena; Sergio Barranco-Medina; Francisca Sevilla; Juan-José Lázaro
Journal:  Plant Physiol       Date:  2010-12-07       Impact factor: 8.340

4.  Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression.

Authors:  Joo Young Huh; Yunghee Kim; Jaeho Jeong; Jehyun Park; Inok Kim; Kyu Ha Huh; Yu Seun Kim; Hyun Ae Woo; Sue Goo Rhee; Kong-Joo Lee; Hunjoo Ha
Journal:  Antioxid Redox Signal       Date:  2011-10-17       Impact factor: 8.401

5.  Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III.

Authors:  You Hyun Noh; Jin Young Baek; Woojin Jeong; Sue Goo Rhee; Tong-Shin Chang
Journal:  J Biol Chem       Date:  2009-01-28       Impact factor: 5.157

6.  Role of peroxiredoxin III in the pathogenesis of pre-eclampsia as evidenced in mice.

Authors:  Lianqin Li; Masuo Obinata; Katsuyoshi Hori
Journal:  Oxid Med Cell Longev       Date:  2010 Jan-Feb       Impact factor: 6.543

7.  Peroxiredoxin 3 is resistant to oxidation-induced apoptosis of Hep-3b cells.

Authors:  Y-G Wang; L Li; C-H Liu; S Hong; M-J Zhang
Journal:  Clin Transl Oncol       Date:  2013-10-09       Impact factor: 3.405

8.  Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells.

Authors:  Goele Aerts; Rafael Arrojo E Drigo; Stijn L J Van Herck; Eva Sammels; Delphine Mirebeau-Prunier; Balázs Gereben; Anikó Zeöld; John W Harney; Stephen A Huang; Michelle A Mulcahey; Serge Van der Geyten; Gert Van den Bergh; Lut Arckens; Veerle M Darras; Ann Marie Zavacki
Journal:  Endocrinology       Date:  2009-10-09       Impact factor: 4.736

9.  Featured Article: Accelerated decline of physical strength in peroxiredoxin-3 knockout mice.

Authors:  Yong-Gang Zhang; Li Wang; Tomonori Kaifu; Jingmin Li; Xiaoyan Li; Lianqin Li
Journal:  Exp Biol Med (Maywood)       Date:  2016-03-31

10.  Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila.

Authors:  Svetlana N Radyuk; Katarzyna Michalak; Vladimir I Klichko; Judith Benes; Igor Rebrin; Rajindar S Sohal; William C Orr
Journal:  Biochem J       Date:  2009-04-15       Impact factor: 3.857
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