Literature DB >> 18542843

On physicalism and downward causation in developmental and cancer biology.

A M Soto1, C Sonnenschein, P A Miquel.   

Abstract

The dominant position in Philosophy of Science contends that downward causation is an illusion. Instead, we argue that downward causation doesn't introduce vicious circles either in physics or in biology. We also question the metaphysical claim that "physical facts fix all the facts." Downward causation does not imply any contradiction if we reject the assumption of the completeness and the causal closure of the physical world that this assertion contains. We provide an argument for rejecting this assumption. Furthermore, this allows us to reconsider the concept of diachronic emergence.

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Year:  2008        PMID: 18542843     DOI: 10.1007/s10441-008-9052-y

Source DB:  PubMed          Journal:  Acta Biotheor        ISSN: 0001-5342            Impact factor:   1.774


  22 in total

1.  Fractal analysis in a systems biology approach to cancer.

Authors:  M Bizzarri; A Giuliani; A Cucina; F D'Anselmi; A M Soto; C Sonnenschein
Journal:  Semin Cancer Biol       Date:  2011-04-13       Impact factor: 15.707

Review 2.  Top-down models in biology: explanation and control of complex living systems above the molecular level.

Authors:  Giovanni Pezzulo; Michael Levin
Journal:  J R Soc Interface       Date:  2016-11       Impact factor: 4.118

Review 3.  Systems biology beyond networks: generating order from disorder through self-organization.

Authors:  K Saetzler; C Sonnenschein; A M Soto
Journal:  Semin Cancer Biol       Date:  2011-05-06       Impact factor: 15.707

4.  Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer.

Authors:  Brook Chernet; Michael Levin
Journal:  J Clin Exp Oncol       Date:  2013

5.  Systems biology and cancer.

Authors:  Ana M Soto; Carlos Sonnenschein; Philip K Maini; Denis Noble
Journal:  Prog Biophys Mol Biol       Date:  2011-08       Impact factor: 3.667

6.  Paradoxes in Carcinogenesis: There Is Light at the End of That Tunnel!

Authors:  Ana M Soto; Carlos Sonnenschein
Journal:  Disrupt Sci Technol       Date:  2013-05-01

7.  An Integrative Approach Toward Biology, Organisms, and Cancer.

Authors:  Carlos Sonnenschein; Ana M Soto
Journal:  Methods Mol Biol       Date:  2018

Review 8.  Toward a theory of organisms: Three founding principles in search of a useful integration.

Authors:  Ana M Soto; Giuseppe Longo; Paul-Antoine Miquel; Maël Montevil; Matteo Mossio; Nicole Perret; Arnaud Pocheville; Carlos Sonnenschein
Journal:  Prog Biophys Mol Biol       Date:  2016-08-04       Impact factor: 3.667

Review 9.  Modeling mammary organogenesis from biological first principles: Cells and their physical constraints.

Authors:  Maël Montévil; Lucia Speroni; Carlos Sonnenschein; Ana M Soto
Journal:  Prog Biophys Mol Biol       Date:  2016-08-18       Impact factor: 3.667

Review 10.  Interpreting endocrine disruption from an integrative biology perspective.

Authors:  Ana M Soto; Beverly S Rubin; Carlos Sonnenschein
Journal:  Mol Cell Endocrinol       Date:  2009-03-09       Impact factor: 4.102

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