Literature DB >> 1854158

Lack of ciprofloxacin ototoxicity after repeated ototopical application.

J Claes1, P J Govaerts, P H Van de Heyning, S Peeters.   

Abstract

The possible side effects of ototopically applied ciprofloxacin on inner ear function were investigated. The hearing function of pigmented guinea pigs was evaluated by daily frequency-specific evoked response audiometry after repeated application of the drug to both ears. Ciprofloxacin appeared to have no statistically significant effect on the hearing thresholds of the experimental animals.

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Year:  1991        PMID： 1854158      PMCID： PMC245150          DOI： 10.1128/AAC.35.5.1014

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  "How I do it"--otology and neurotology. A specific issue and its solution. Medical management of the chronic draining ear.

Authors:  J S Supance; C D Bluestone
Journal:  Laryngoscope       Date:  1983-05       Impact factor: 3.325

Review 2.  Aminoglycoside-induced ototoxicity.

Authors:  P J Govaerts; J Claes; P H van de Heyning; P G Jorens; J Marquet; M E De Broe
Journal:  Toxicol Lett       Date:  1990-08       Impact factor: 4.372

3.  Ototoxicity of ear drops in patients suffering from chronic otitis media.

Authors:  L Podoshin; M Fradis; J Ben David
Journal:  J Laryngol Otol       Date:  1989-01       Impact factor: 1.469

4.  Ototoxicity of neomycin and its penetration through the round window membrane into the perilymph.

Authors:  T Harada; M Iwamori; Y Nagai; Y Nomura
Journal:  Ann Otol Rhinol Laryngol       Date:  1986 Jul-Aug       Impact factor: 1.547

5.  In vitro activity of ciprofloxacin compared with those of other new fluorinated piperazinyl-substituted quinoline derivatives.

Authors:  D L Van Caekenberghe; S R Pattyn
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191
  5 in total
  6 in total

1.  Protective effects of local administration of ciprofloxacin on the risk of pneumococcal meningitis after cochlear implantation.

Authors:  Benjamin P C Wei; Roy M Robins-Browne; Robert K Shepherd; Kristy Azzopardi; Graeme M Clark; Stephen J O'Leary
Journal:  Laryngoscope       Date:  2006-12       Impact factor: 3.325

2.  Tinnitus and ciprofloxacin.

Authors:  J Paul; N M Brown
Journal:  BMJ       Date:  1995-07-22

3.  Evaluation of the effectiveness of topical ciprofloxacin and prednisolone in the prevention of myringosclerosis.

Authors:  Necmi Arslan; Davut Tepe; Eren Taştan; Munir Demirci; Muzaffer Caydere; Huseyin Ustun; Haldun Oguz
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-12-25       Impact factor: 2.503

4.  Effect of nystatin on Guinea Pigs' inner ear.

Authors:  Owen Woods; Issam Saliba
Journal:  Neurotox Res       Date:  2011-03-08       Impact factor: 3.911

5.  Susceptibility of microorganisms isolated from chronic suppurative otitis media to ciprofloxacin.

Authors:  A Altuntas; A Aslan; N Eren; A Unal; Y Nalca
Journal:  Eur Arch Otorhinolaryngol       Date:  1996       Impact factor: 2.503

6.  The effect of topical ciprofloxacin and steroid-containing ear drops for chronic suppurative otitis media on the internal ear.

Authors:  Zeliha Kapusuz; Erol Keles; Hayrettin Cengiz Alpay; Turgut Karlidag; Irfan Kaygusuz; Ali Kemal Uzunlar; Israfil Orhan; Sinasi Yalcin
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-01       Impact factor: 2.503
  6 in total

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