Literature DB >> 18541430

Simultaneous arthroscopic implantation of autologous chondrocytes and high tibial osteotomy for tibial chondral defects in the varus knee.

Francesco Franceschi1, Umile Giuseppe Longo, Laura Ruzzini, Andrea Marinozzi, Nicola Maffulli, Vincenzo Denaro.   

Abstract

There is no consensus on the ideal management of patients with chondral defects of the medial tibial plateau and varus malalignment of the knee. We performed a cohort study to evaluate the outcome of patients affected by these conditions, who underwent arthroscopic implantation of autologous chondrocytes and a medial opening wedge high tibial osteotomy. Eight patients (four men and four women; mean age, 50 years, range: 42 to 58) with chondral defects of the medial tibial plateau in a varus knee underwent arthroscopic implantations of autologous chondrocytes in conjunction with a medial opening wedge osteotomy. At final post-operative follow up of 28 months following the index procedure, the post-operative scores were improved for the IKDC score (four patients abnormal and four patients severely abnormal to four patients normal, three patients nearly normal and one patient abnormal), Lysholm score (65.7 range 49-88 to 94.6 range 89-100), Tegner score (3.7 range 3-5 to 7 range 5-8) and VAS score (7.2 to 2.0). In conclusion, the association of arthroscopic implantation of autologous chondrocytes with a medial opening wedge osteotomy of the proximal tibia is a viable option for the management of chondral defects in varus knees.

Entities:  

Mesh:

Year:  2008        PMID: 18541430     DOI: 10.1016/j.knee.2008.04.007

Source DB:  PubMed          Journal:  Knee        ISSN: 0968-0160            Impact factor:   2.199


  23 in total

Review 1.  The use of the Tegner Activity Scale for articular cartilage repair of the knee: a systematic review.

Authors:  Karen Hambly
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-11-13       Impact factor: 4.342

2.  Hyaluronic acid-binding insulin-like growth factor-1: Creation of a gene encoding a bifunctional fusion protein.

Authors:  Shuiliang Shi; Congrong Wang; Stephen B Trippel
Journal:  Mol Biol Rep       Date:  2020-12-02       Impact factor: 2.316

3.  Degree of axis correction in valgus high tibial osteotomy: proposal of an individualised approach.

Authors:  Matthias J Feucht; Philipp Minzlaff; Tim Saier; Matthias Cotic; Norbert P Südkamp; Philipp Niemeyer; Andreas B Imhoff; Stefan Hinterwimmer
Journal:  Int Orthop       Date:  2014-07-10       Impact factor: 3.075

4.  Scanty integration of osteochondral allografts cryopreserved at low temperatures with dimethyl sulfoxide.

Authors:  Francisco Forriol; Umile Giuseppe Longo; Eduardo Alvarez; Stefano Campi; Purificacion Ripalda; Carla Rabitti; Nicola Maffulli; Vincenzo Denaro
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-11-06       Impact factor: 4.342

5.  Osteochondral Allograft Transplantation and Opening Wedge Tibial Osteotomy: Clinical Results of a Combined Single Procedure.

Authors:  Albert C Hsu; Luis E P Tirico; Abraham G Lin; Pamela A Pulido; William D Bugbee
Journal:  Cartilage       Date:  2017-05-22       Impact factor: 4.634

6.  Microfracture for chondral defects of the talus: maintenance of early results at midterm follow-up.

Authors:  Christoph Becher; Arne Driessen; Thomas Hess; Umile Giuseppe Longo; Nicola Maffulli; Hajo Thermann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-02-04       Impact factor: 4.342

7.  No evidence for combining cartilage treatment and knee osteotomy in osteoarthritic joints: a systematic literature review.

Authors:  G Filardo; S Zaffagnini; R De Filippis; F Perdisa; L Andriolo; C Candrian
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-02-16       Impact factor: 4.342

8.  Customized post-operative alignment improves clinical outcome following medial open-wedge osteotomy.

Authors:  Lisa Hohloch; Suchung Kim; Julian Mehl; Jörn Zwingmann; Matthias J Feucht; Helge Eberbach; Philipp Niemeyer; Norbert Südkamp; Gerrit Bode
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-10-03       Impact factor: 4.342

9.  Clinical outcome and return to work following single-stage combined autologous chondrocyte implantation and high tibial osteotomy.

Authors:  Gerrit Bode; Peter Ogon; Jan Pestka; Jörn Zwingmann; Matthias Feucht; Norbert Südkamp; Philipp Niemeyer
Journal:  Int Orthop       Date:  2014-10-10       Impact factor: 3.075

10.  Combination of High Tibial Osteotomy and Autologous Bone Marrow Derived Cell Implantation in Early Osteoarthritis of Knee: A Preliminary Study.

Authors:  Marco Cavallo; Sayyed-Hadi Sayyed-Hosseinian; Alessandro Parma; Roberto Buda; Massimiliano Mosca; Sandro Giannini
Journal:  Arch Bone Jt Surg       Date:  2018-03
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.