BACKGROUND: The observation that bipolar disorders frequently go unrecognized has prompted the development of screening instruments designed to improve the identification of bipolarity in clinical and non-clinical samples. Starting from a lifetime approach, researchers of the Spectrum Project developed the Mood Spectrum Self-Report (MOODS-SR) that assesses threshold-level manifestations of unipolar and bipolar mood psychopathology, but also atypical symptoms, behavioral traits and temperamental features. The aim of the present study is to examine the structure of mania/hypomania using 68 items of the MOODS-SR that explore cognitive, mood and energy/activity features associated with mania/hypomania. METHODS: A data pool of 617 patients with bipolar disorders, recruited at Pittsburgh and Pisa, Italy was used for this purpose. Classical exploratory factor analysis, based on a tetrachoric matrix, was carried out on the 68 items, followed by an Item Response Theory (IRT)-based factor analytic approach. RESULTS: Nine factors were initially identified, that include Psychomotor Activation, Creativity, Mixed Instability, Sociability/Extraversion, Spirituality/Mysticism/Psychoticism, Mixed Irritability, Inflated Self-esteem, Euphoria, Wastefulness/Recklessness, and account overall for 56.4% of the variance of items. In a subsequent IRT-based bi-factor analysis, only five of them (Psychomotor Activation, Mixed Instability, Spirituality/Mysticism/Psychoticism, Mixed Irritability, Euphoria) were retained. CONCLUSIONS: Our data confirm the central role of Psychomotor Activation in mania/hypomania and support the definitions of pure manic (Psychomotor Activation and Euphoria) and mixed manic (Mixed Instability and Mixed Irritability) components, bearing the opportunity to identify patients with specific profiles for a better clinical and neurobiological definition.
BACKGROUND: The observation that bipolar disorders frequently go unrecognized has prompted the development of screening instruments designed to improve the identification of bipolarity in clinical and non-clinical samples. Starting from a lifetime approach, researchers of the Spectrum Project developed the Mood Spectrum Self-Report (MOODS-SR) that assesses threshold-level manifestations of unipolar and bipolar mood psychopathology, but also atypical symptoms, behavioral traits and temperamental features. The aim of the present study is to examine the structure of mania/hypomania using 68 items of the MOODS-SR that explore cognitive, mood and energy/activity features associated with mania/hypomania. METHODS: A data pool of 617 patients with bipolar disorders, recruited at Pittsburgh and Pisa, Italy was used for this purpose. Classical exploratory factor analysis, based on a tetrachoric matrix, was carried out on the 68 items, followed by an Item Response Theory (IRT)-based factor analytic approach. RESULTS: Nine factors were initially identified, that include Psychomotor Activation, Creativity, Mixed Instability, Sociability/Extraversion, Spirituality/Mysticism/Psychoticism, Mixed Irritability, Inflated Self-esteem, Euphoria, Wastefulness/Recklessness, and account overall for 56.4% of the variance of items. In a subsequent IRT-based bi-factor analysis, only five of them (Psychomotor Activation, Mixed Instability, Spirituality/Mysticism/Psychoticism, Mixed Irritability, Euphoria) were retained. CONCLUSIONS: Our data confirm the central role of Psychomotor Activation in mania/hypomania and support the definitions of pure manic (Psychomotor Activation and Euphoria) and mixed manic (Mixed Instability and Mixed Irritability) components, bearing the opportunity to identify patients with specific profiles for a better clinical and neurobiological definition.
Authors: Ana González-Pinto; Ana Aldama; Asunción González Pinto; Fernando Mosquera; José Luis Pérez de Heredia; Javier Ballesteros; Miguel Gutiérrez Journal: Eur Psychiatry Date: 2004-08 Impact factor: 5.361
Authors: A González-Pinto; J Ballesteros; A Aldama; J L Pérez de Heredia; M Gutierrez; F Mosquera; A González-Pinto Journal: J Affect Disord Date: 2003-09 Impact factor: 4.839
Authors: S Calugi; G B Cassano; A Litta; P Rucci; A Benvenuti; M Miniati; L Lattanzi; V Mantua; V Lombardi; A Fagiolini; E Frank Journal: J Affect Disord Date: 2010-09-15 Impact factor: 4.839
Authors: G B Cassano; A Benvenuti; M Miniati; S Calugi; M Mula; L Maggi; P Rucci; A Fagiolini; F Perris; E Frank Journal: J Affect Disord Date: 2008-10-22 Impact factor: 4.839
Authors: Stephen F Smagula; Robert T Krafty; Julian F Thayer; Daniel J Buysse; Martica H Hall Journal: J Psychiatr Res Date: 2018-04-21 Impact factor: 4.791
Authors: Claudia Carmassi; P Stratta; E Calderani; C A Bertelloni; M Menichini; E Massimetti; A Rossi; L Dell'Osso Journal: J Relig Health Date: 2016-04
Authors: E Frank; G B Cassano; P Rucci; W K Thompson; H C Kraemer; A Fagiolini; L Maggi; D J Kupfer; M K Shear; P R Houck; S Calugi; V J Grochocinski; P Scocco; J Buttenfield; R N Forgione Journal: Psychol Med Date: 2010-04-12 Impact factor: 7.723
Authors: Antonella Benvenuti; Paola Rucci; Simona Calugi; Giovanni B Cassano; Mario Miniati; Ellen Frank Journal: Int Clin Psychopharmacol Date: 2010-03 Impact factor: 1.659