Literature DB >> 18538650

A bitter PP1 fights the sweet polo.

Vincent Archambault1, Feng Chen, David M Glover.   

Abstract

In a recent paper in Developmental Cell, Yamashiro et al. (2008) report that the PP1 regulatory subunit MYPT1 interacts with PLK1 and antagonizes essential mitotic functions of PLK1, at least in part by promoting the dephosphorylation of PLK1 at Thr210.

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Year:  2008        PMID: 18538650     DOI: 10.1016/j.molcel.2008.05.012

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  3 in total

1.  High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888.

Authors:  Susan K Lyman; Suzanne C Crawley; Ruoyu Gong; Joanne I Adamkewicz; Garth McGrath; Jason Y Chew; Jennifer Choi; Charles R Holst; Leanne H Goon; Scott A Detmer; Jana Vaclavikova; Mary E Gerritsen; Robert A Blake
Journal:  PLoS One       Date:  2011-03-07       Impact factor: 3.240

2.  Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase.

Authors:  Sourav Banerjee; Anna Zagórska; Maria Deak; David G Campbell; Alan R Prescott; Dario R Alessi
Journal:  Biochem J       Date:  2014-07-15       Impact factor: 3.857

3.  Targeting phosphatases in cancer: suppression of many versus the ablation of one.

Authors:  Brandon M D'Arcy; Aishwarya Prakash; Richard E Honkanen
Journal:  Oncotarget       Date:  2019-11-12
  3 in total

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