Literature DB >> 18538435

IVIVC of controlled release formulations: physiological-dynamical reasons for their failure.

A Dokoumetzidis1, P Macheras.   

Abstract

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Year:  2008        PMID： 18538435     DOI： 10.1016/j.jconrel.2008.04.005

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


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  4 in total

1.  Elucidating the role of dose in the biopharmaceutics classification of drugs: the concepts of critical dose, effective in vivo solubility, and dose-dependent BCS.

Authors:  Georgia Charkoftaki; Aristides Dokoumetzidis; Georgia Valsami; Panos Macheras
Journal:  Pharm Res       Date:  2012-07-04       Impact factor: 4.200

2.  Controlled release of ropinirole hydrochloride from a multiple barrier layer tablet dosage form: effect of polymer type on pharmacokinetics and IVIVC.

Authors:  Nikhil Malewar; Makarand Avachat; Varsha Pokharkar; Shirish Kulkarni
Journal:  AAPS PharmSciTech       Date:  2013-07-30       Impact factor: 3.246

3.  A novel beads-based dissolution method for the in vitro evaluation of extended release HPMC matrix tablets and the correlation with the in vivo data.

Authors:  Uroš Klančar; Boštjan Markun; Saša Baumgartner; Igor Legen
Journal:  AAPS J       Date:  2012-11-28       Impact factor: 4.009

4.  Determining the polymer threshold amount for achieving robust drug release from HPMC and HPC matrix tablets containing a high-dose BCS class I model drug: in vitro and in vivo studies.

Authors:  Uroš Klančar; Saša Baumgartner; Igor Legen; Polona Smrdel; Nataša Jeraj Kampuš; Dejan Krajcar; Boštjan Markun; Klemen Kočevar
Journal:  AAPS PharmSciTech       Date:  2014-10-18       Impact factor: 3.246
  4 in total

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