Literature DB >> 18536949

The role of the ERG in the diagnosis and treatment of Age-Related Macular Degeneration.

Christina Gerth1.   

Abstract

Age-related macular degeneration (AMD) is affecting an increasing number of people, with 2.95 million people estimated to be affected in the USA by 2020. Possible preventive agents, such as vitamins and supplements have been studied and new treatment options for AMD have been developed in recent years. What role does electrophysiology play as a sensitive outcome measure? The most commonly used tests are the full-field electroretinogram (ffERG) and the multifocal ERG (mfERG). Test results from patients with AMD and reduced central vision need special attention in respect to fixation pattern, age-matched control data, and retinal luminance. Advantages, disadvantages and limitations of techniques will be considered, together with a review of published studies.

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Year:  2008        PMID: 18536949     DOI: 10.1007/s10633-008-9133-x

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  51 in total

1.  Change in full-field ERGs after macular translocation surgery with 360 degrees retinotomy.

Authors:  Hiroko Terasaki; Yozo Miyake; Toshimitsu Suzuki; Takashi Niwa; Chang-Hua Piao; Satoshi Suzuki; Makoto Nakamura; Mineo Kondo
Journal:  Invest Ophthalmol Vis Sci       Date:  2002-02       Impact factor: 4.799

2.  [Testing central retinal function with multifocal electroretinography before and after photodynamic therapy].

Authors:  K Rüther; K Breidenbach; R Schwartz; A Hassenstein; G Richard
Journal:  Ophthalmologe       Date:  2003-06       Impact factor: 1.059

3.  Cone- and rod-mediated multifocal electroretinogram in early age-related maculopathy.

Authors:  B Feigl; B Brown; J Lovie-Kitchin; P Swann
Journal:  Eye (Lond)       Date:  2005-04       Impact factor: 3.775

Review 4.  The natural history and prognosis of neovascular age-related macular degeneration: a systematic review of the literature and meta-analysis.

Authors:  Tien Y Wong; Tien Wong; Usha Chakravarthy; Ronald Klein; Paul Mitchell; Gergana Zlateva; Ronald Buggage; Kyle Fahrbach; Corey Probst; Isabella Sledge
Journal:  Ophthalmology       Date:  2007-08-06       Impact factor: 12.079

5.  Ocular changes after photodynamic therapy.

Authors:  Radouil Tzekov; Ton Lin; Kai-Ming Zhang; Brittany Jackson; Adelekan Oyejide; Werhner Orilla; Amol D Kulkarni; Baruch D Kuppermann; Larry Wheeler; James Burke
Journal:  Invest Ophthalmol Vis Sci       Date:  2006-01       Impact factor: 4.799

6.  Intravitreal use of bevacizumab (Avastin) for choroidal neovascularization due to ARMD: a preliminary multifocal-ERG and OCT study. Multifocal-ERG after use of bevacizumab in ARMD.

Authors:  Marilita M Moschos; Dimitrios Brouzas; Michael Apostolopoulos; Chrysanthi Koutsandrea; Eleni Loukianou; Michael Moschos
Journal:  Doc Ophthalmol       Date:  2007-01-10       Impact factor: 2.379

7.  Electrophysiologic findings after intravitreal bevacizumab (Avastin) treatment.

Authors:  Raj K Maturi; Laura A Bleau; Donald L Wilson
Journal:  Retina       Date:  2006-03       Impact factor: 4.256

8.  The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study.

Authors:  R Klein; B E Klein; S C Jensen; S M Meuer
Journal:  Ophthalmology       Date:  1997-01       Impact factor: 12.079

9.  Impact of aging and age-related maculopathy on activation of the a-wave of the rod-mediated electroretinogram.

Authors:  Gregory R Jackson; Gerald McGwin; Janice M Phillips; Ronald Klein; Cynthia Owsley
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-09       Impact factor: 4.799

10.  The changes of pattern electroretinography at the early stage of photodynamic therapy.

Authors:  Ayse Oner; Sarper Karakucuk; Ertugrul Mirza; Kuddusi Erkilic
Journal:  Doc Ophthalmol       Date:  2006-03-02       Impact factor: 2.379

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  18 in total

Review 1.  Animal models of age related macular degeneration.

Authors:  Mark E Pennesi; Martha Neuringer; Robert J Courtney
Journal:  Mol Aspects Med       Date:  2012-06-15

2.  Effects of luminance combinations on the characteristics of the global flash multifocal electroretinogram (mfERG).

Authors:  Jenny C Y Lung; Henry H L Chan
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-03-20       Impact factor: 3.117

Review 3.  The electroretinogram: a useful tool for evaluating age-related macular disease?

Authors:  Emma J Berrow; Hannah E Bartlett; Frank Eperjesi; Jonathan M Gibson
Journal:  Doc Ophthalmol       Date:  2010-03-16       Impact factor: 2.379

4.  Systemic human CR2-targeted complement alternative pathway inhibitor ameliorates mouse laser-induced choroidal neovascularization.

Authors:  Bärbel Rohrer; Beth Coughlin; Mausumi Bandyopadhyay; V Michael Holers
Journal:  J Ocul Pharmacol Ther       Date:  2012-02-06       Impact factor: 2.671

5.  Multimodal assessment of microscopic morphology and retinal function in patients with geographic atrophy.

Authors:  Athanasios Panorgias; Robert J Zawadzki; Arlie G Capps; Allan A Hunter; Lawrence S Morse; John S Werner
Journal:  Invest Ophthalmol Vis Sci       Date:  2013-06-26       Impact factor: 4.799

6.  [Multifocal electroretinography for therapeutic effect evaluation of intravitreal injection Lucentis for wet age-related macular degeneration].

Authors:  Rui-Hong Ju; Man-Sha He; Jin-Tong Hou; Meng-Yuan Li; Jing-Lin Zhang; Zhe-Ming Wu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-07-20

7.  The value of multifocal electroretinography to predict progressive visual acuity loss in early AMD.

Authors:  L Ambrosio; G Ambrosio; G Nicoletti; G de Crecchio; B Falsini
Journal:  Doc Ophthalmol       Date:  2015-07-02       Impact factor: 2.379

8.  Cone implicit time as a predictor of visual outcome in macular hole surgery.

Authors:  Sten Andréasson; Fredrik Ghosh
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-05-02       Impact factor: 3.117

9.  A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration.

Authors:  Venkata R M Chavali; Naheed W Khan; Catherine A Cukras; Dirk-Uwe Bartsch; Monica M Jablonski; Radha Ayyagari
Journal:  Hum Mol Genet       Date:  2011-02-24       Impact factor: 6.150

10.  Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

Authors:  Peng Hu; Rolf Herrmann; Amanda Bednar; Peter Saloupis; Mary A Dwyer; Ping Yang; Xiaoping Qi; Russell S Thomas; Glenn J Jaffe; Michael E Boulton; Donald P McDonnell; Goldis Malek
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-08       Impact factor: 11.205

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