Literature DB >> 18536528

AACR Annual Meeting 2008: autophagy in the forefront of cancer research.

Vassiliki Karantza-Wadsworth1.   

Abstract

The 2008 American Association for Cancer Research (AACR) Annual Meeting was held in San Diego, CA, April 12-16, 2008 (http:// www.aacr.org/home/scientists/meetings--workshops/annual-meeting-2008.aspx). More than 17,000 scientists from 60 countries participated in this meeting that was organized by AACR, the oldest and largest organization in the world focused on cancer research. The scientific presentations included more than 6,000 abstracts and 500 invited talks on new and significant discoveries in basic, clinical, and translational cancer research. Autophagy, as pertaining to tumorigenesis and response to anticancer therapies, was undoubtedly a "hot topic" in this meeting. An educational session, a forum, a minisymposium and several other talks dispersed in different sessions had a strong focus on autophagy. All autophagy-related presentations were very well attended and stimulated lively discussions, clearly indicating that the scientific community is greatly interested in this rapidly-progressing area of research.

Entities:  

Mesh:

Year:  2008        PMID: 18536528      PMCID: PMC3155289     

Source DB:  PubMed          Journal:  Autophagy        ISSN: 1554-8627            Impact factor:   16.016


  10 in total

1.  Growth factor regulation of autophagy and cell survival in the absence of apoptosis.

Authors:  Julian J Lum; Daniel E Bauer; Mei Kong; Marian H Harris; Chi Li; Tullia Lindsten; Craig B Thompson
Journal:  Cell       Date:  2005-01-28       Impact factor: 41.582

2.  Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Authors:  Masaaki Komatsu; Satoshi Waguri; Masato Koike; Yu-Shin Sou; Takashi Ueno; Taichi Hara; Noboru Mizushima; Jun-Ichi Iwata; Junji Ezaki; Shigeo Murata; Jun Hamazaki; Yasumasa Nishito; Shun-Ichiro Iemura; Tohru Natsume; Toru Yanagawa; Junya Uwayama; Eiji Warabi; Hiroshi Yoshida; Tetsuro Ishii; Akira Kobayashi; Masayuki Yamamoto; Zhenyu Yue; Yasuo Uchiyama; Eiki Kominami; Keiji Tanaka
Journal:  Cell       Date:  2007-12-14       Impact factor: 41.582

3.  Autophagy suppresses tumor progression by limiting chromosomal instability.

Authors:  Robin Mathew; Sameera Kongara; Brian Beaudoin; Cristina M Karp; Kevin Bray; Kurt Degenhardt; Guanghua Chen; Shengkan Jin; Eileen White
Journal:  Genes Dev       Date:  2007-05-17       Impact factor: 11.361

4.  Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma.

Authors:  Ravi K Amaravadi; Duonan Yu; Julian J Lum; Thi Bui; Maria A Christophorou; Gerard I Evan; Andrei Thomas-Tikhonenko; Craig B Thompson
Journal:  J Clin Invest       Date:  2007-01-18       Impact factor: 14.808

5.  Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.

Authors:  Kurt Degenhardt; Robin Mathew; Brian Beaudoin; Kevin Bray; Diana Anderson; Guanghua Chen; Chandreyee Mukherjee; Yufang Shi; Céline Gélinas; Yongjun Fan; Deirdre A Nelson; Shengkan Jin; Eileen White
Journal:  Cancer Cell       Date:  2006-07       Impact factor: 31.743

Review 6.  Role of autophagy in cancer.

Authors:  Robin Mathew; Vassiliki Karantza-Wadsworth; Eileen White
Journal:  Nat Rev Cancer       Date:  2007-12       Impact factor: 60.716

7.  Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.

Authors:  Kirsteen H Maclean; Frank C Dorsey; John L Cleveland; Michael B Kastan
Journal:  J Clin Invest       Date:  2008-01       Impact factor: 14.808

8.  Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance.

Authors:  Jennifer S Carew; Steffan T Nawrocki; Charissa N Kahue; Hui Zhang; Chunying Yang; Linda Chung; Janet A Houghton; Peng Huang; Francis J Giles; John L Cleveland
Journal:  Blood       Date:  2007-03-15       Impact factor: 22.113

9.  Entosis: it's a cell-eat-cell world.

Authors:  Eileen White
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

10.  Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis.

Authors:  Vassiliki Karantza-Wadsworth; Shyam Patel; Olga Kravchuk; Guanghua Chen; Robin Mathew; Shengkan Jin; Eileen White
Journal:  Genes Dev       Date:  2007-07-01       Impact factor: 11.361

  10 in total

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