Literature DB >> 18536154

Lipophilicity of thiobarbiturates determined by TLC.

Elzbieta Kepczyńska1, Ewa Obłoza, Anna Stasiewicz-Urban, Jacek Bojarski, Alina Pyka.   

Abstract

Lipophilicty of 29 thiobarbituric acid derivatives were assessed by reversed-phase thin-layer chromatography using methanol: water mixtures as a mobile phase. A linear relationship was found between RM values and methanol concentrations in the mobile phase. The retention parameter, RM0, was related to theoretical partition coefficients calculated by means of different theoretical procedures (AlogPs, IAlogP, miLogP, logPKowwin, xlogP).

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Year:  2007        PMID: 18536154

Source DB:  PubMed          Journal:  Acta Pol Pharm        ISSN: 0001-6837            Impact factor:   0.330


  2 in total

1.  Theoretical and experimental study on lipophilicity and wound healing activity of ginger compounds.

Authors:  Mohammed Afroz Bakht; Mohammed F Alajmi; Perwez Alam; Aftab Alam; Prawez Alam; Tariq Mohammed Aljarba
Journal:  Asian Pac J Trop Biomed       Date:  2014-04

2.  New methodology for the synthesis of thiobarbiturates mediated by manganese(III) acetate.

Authors:  Ahlem Bouhlel; Christophe Curti; Patrice Vanelle
Journal:  Molecules       Date:  2012-04-10       Impact factor: 4.411

  2 in total

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