Literature DB >> 18534315

Management of femoral fracture in a patient with essential thrombocythemia treated with plateletpheresis and intramedullary rod fixation, followed by hydroxyurea: a case report.

Richard F Edlich1, William B Long, Amy A Cochran, Angela R Kelley, Dayna R Woode, Jill Amanda Greene, Gary W Takahashi.   

Abstract

We describe the management of a patient with a femoral fracture who had asymptomatic essential thrombocythemia. When the diagnosis of essential thrombocythemia was made, the patient was treated with plateletpheresis to reduce the platelet count before intramedullary rod fixation of his fracture. His postoperative management included the examination of his peripheral blood as well as bone marrow, which confirmed that the cause of his elevated platelet count was due to JAK2 V617F mutation that is treated by hydroxyurea and aspirin after being discharged from the hospital.

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Year:  2008        PMID: 18534315     DOI: 10.1016/j.ajem.2007.09.025

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  2 in total

Review 1.  The role of thrombocytapheresis in the contemporary management of hyperthrombocytosis in myeloproliferative neoplasms: A case-based review.

Authors:  Prajwal Boddu; Lorenzo Falchi; Chitra Hosing; Kate Newberry; Prithviraj Bose; Srdan Verstovsek
Journal:  Leuk Res       Date:  2017-03-22       Impact factor: 3.156

Review 2.  Abdominal surgery in patients with essential thrombocythemia: A case report and systematic review of literature.

Authors:  Yi Zhu; HongGang Jiang; ZhiHeng Chen; BoHao Lu; JiaMing Wu
Journal:  Medicine (Baltimore)       Date:  2017-11       Impact factor: 1.817

  2 in total

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