Literature DB >> 185321

The effects of cytochalasin and colchicine on interferon production.

Y Ito, Y Nishiyama, K Shimokata, Y Kimura, I Nagata, A Kunii.   

Abstract

The present study was undertaken to investigate the mechanism of interferon production by mouse spleen cells co-cultivated with BHK-HVJ cells, i.e. baby hamster kidney cells persistently infected with the HVJ (or Sendai) strain of para-influenza I virus. Cytochalasin B appears to inhibit an early stage in the process and colchicine a relatively late stage. It is suggested that microfilaments and microtubules may play in important role at an initial stage of interferon production in this system.

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Year:  1976        PMID： 185321     DOI： 10.1099/0022-1317-33-1-1

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  5 in total

1.  Search for Sendai 6/94 viral RNA in the antigen-free cell line Cl-C-2 isolated from human multiple sclerosis brain tissue.

Authors:  W J Neubert; P H Hofschneider; H Koprowski
Journal:  Infect Immun       Date:  1983-08       Impact factor: 3.441

2.  Mechanism of immune interferon production in vitro: interaction between immune interferon-producing cells and antigenic cells.

Authors:  Y Ito; H Aoki; Y Kimura; K Shimokata; K Maeno
Journal:  Infect Immun       Date:  1981-03       Impact factor: 3.441

3.  Synergistic Signaling of TLR and IFNα/β Facilitates Escape of IL-18 Expression from Endotoxin Tolerance.

Authors:  Emely Verweyen; Dirk Holzinger; Toni Weinhage; Claas Hinze; Helmut Wittkowski; Peter Pickkers; Sabrin Albeituni; Katherine Verbist; Kim E Nichols; Grant Schulert; Alexei Grom; Dirk Foell; Christoph Kessel
Journal:  Am J Respir Crit Care Med       Date:  2020-03-01       Impact factor: 21.405

4.  Cell Cycle Arrest in G2/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression.

Authors:  Christian Bressy; Gaith N Droby; Bryant D Maldonado; Nury Steuerwald; Valery Z Grdzelishvili
Journal:  J Virol       Date:  2019-02-05       Impact factor: 5.103

Review 5.  Induction of interferon by virus glycoprotein(s) in lymphoid cells through interaction with the cellular receptors via lectin-like action: an alternative interferon induction mechanism.

Authors:  Y Ito
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574
  5 in total

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