Literature DB >> 18523412

Hair follicles--an efficient storage and penetration pathway for topically applied substances. Summary of recent results obtained at the Center of Experimental and Applied Cutaneous Physiology, Charité -Universitätsmedizin Berlin, Germany.

J Lademann1, F Knorr, H Richter, U Blume-Peytavi, A Vogt, C Antoniou, W Sterry, A Patzelt.   

Abstract

In the past, it was assumed that the intercellular route was the only relevant penetration pathway for topically applied substances. Recent results on follicular penetration obtained at the Center for Experimental and Applied Cutaneous Physiology, Charité - Universitätsmedizin Berlin, Germany, emphasize that the hair follicles represent a highly relevant and efficient penetration pathway and reservoir for topically applied substances. (c) 2008 S. Karger AG, Basel.

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Substances:

Year:  2008        PMID: 18523412     DOI: 10.1159/000131079

Source DB:  PubMed          Journal:  Skin Pharmacol Physiol        ISSN: 1660-5527            Impact factor:   3.479


  21 in total

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Review 2.  [How safe are nanoparticles?].

Authors:  J Lademann; M Meinke; W Sterry; A Patzelt
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3.  Permeation of topically applied caffeine through human skin--a comparison of in vivo and in vitro data.

Authors:  Sindy Trauer; Alexa Patzelt; Nina Otberg; Fanny Knorr; Christel Rozycki; Gabor Balizs; Rolf Büttemeyer; Michael Linscheid; Manfred Liebsch; Jürgen Lademann
Journal:  Br J Clin Pharmacol       Date:  2009-08       Impact factor: 4.335

4.  Video-rate molecular imaging in vivo with stimulated Raman scattering.

Authors:  Brian G Saar; Christian W Freudiger; Jay Reichman; C Michael Stanley; Gary R Holtom; X Sunney Xie
Journal:  Science       Date:  2010-12-03       Impact factor: 47.728

5.  Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man.

Authors:  Xin Liu; Jeff E Grice; Juergen Lademann; Nina Otberg; Sindy Trauer; Alexa Patzelt; Michael S Roberts
Journal:  Br J Clin Pharmacol       Date:  2011-11       Impact factor: 4.335

6.  Investigation of polylactic acid (PLA) nanoparticles as drug delivery systems for local dermatotherapy.

Authors:  Fiorenza Rancan; Dimitrios Papakostas; Sabrina Hadam; Steffen Hackbarth; Thierry Delair; Charlotte Primard; Bernard Verrier; Wolfram Sterry; Ulrike Blume-Peytavi; Annika Vogt
Journal:  Pharm Res       Date:  2009-06-17       Impact factor: 4.200

Review 7.  Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery.

Authors:  Pinaki Desai; Ram R Patlolla; Mandip Singh
Journal:  Mol Membr Biol       Date:  2010-10       Impact factor: 2.857

8.  The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro.

Authors:  Jessica Stahl; Michael Braun; Joerg Siebert; Manfred Kietzmann
Journal:  BMC Vet Res       Date:  2011-08-11       Impact factor: 2.741

9.  Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin.

Authors:  Gabriel Serrano; Patricia Almudéver; Juan M Serrano; Julio Cortijo; Carmen Faus; Magda Reyes; Inmaculada Expósito; Ana Torrens; Fernando Millán
Journal:  Clin Cosmet Investig Dermatol       Date:  2015-06-26

10.  Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.

Authors:  Andria Constantinou; Katarzyna Polak-Witka; Marios Tomazou; Anastasis Oulas; Varvara Kanti; Rolf Schwarzer; Johannes Helmuth; Anke Edelmann; Ulrike Blume-Peytavi; George M Spyrou; Annika Vogt
Journal:  Biomedicines       Date:  2021-03-07
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