Literature DB >> 185233

Chemical characterization of ectopic ACTH purified from a malignant thymic carcinoid tumor.

P J Lowry, L H Rees, S Tomlin, G Gillies, J Landon.   

Abstract

ACTH was purified from thymic tumor associated with ectopic ACTH production by gel filtration and ion exchange chromatography. Amino acid composition and C- and N-terminal analyses indicated that this tumor ACTH was comprised of the 2-38 sequence of authentic pituitary ACTH. The observations suggest that the mode of cleavage of this tumor ACTH from its precursor is different from that of pituitary ACTH.

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Year:  1976        PMID： 185233     DOI： 10.1210/jcem-43-4-831

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  8 in total

Review 1.  Primary thymic carcinoid with Cushing's syndrome.

Authors:  G Wollensak; E W Herbst; A Beck; H E Schaefer
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992

2.  Neuroendocrine ACTH-producing tumor of the thymus--experience with 12 patients over 25 years.

Authors:  Nicola M Neary; Ariel Lopez-Chavez; Brent S Abel; Alison M Boyce; Nicholas Schaub; King Kwong; Constantine A Stratakis; Cesar A Moran; Giuseppe Giaccone; Lynnette K Nieman
Journal:  J Clin Endocrinol Metab       Date:  2012-04-16       Impact factor: 5.958

Review 3.  Cell differentiation and the biological significance of inappropriate tumour products.

Authors:  M L Ellison
Journal:  Proc R Soc Med       Date:  1977-12

4.  Corticotropin, lipotropin, and beta-endorphin production by a human nonpituitary tumor in culture: evidence for a common precursor.

Authors:  X Y Bertagna; W E Nicholson; G D Sorenson; O S Pettengill; C D Mount; D N Orth
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

5.  Common precursor to corticotropins and endorphins.

Authors:  R E Mains; B A Eipper; N Ling
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

6.  Immunohistochemical and immunoelectron-microscopic study of pituitary adenomas associated with Cushing's disease. A report of 13 cases.

Authors:  C Charpin; J Hassoun; C Oliver; P Jaquet; B Argemi; F Grisoli; M Toga
Journal:  Am J Pathol       Date:  1982-10       Impact factor: 4.307

7.  Diagnosis of lung carcinoid with cutaneous hyperpigmentation eight years after bilateral adrenalectomy.

Authors:  M D Rodriguez Vaca; M Angel; I Halperin; J Freixenet; M Marti; M J Martinez Osaba; J Sanchez Lloret; A Palacin; E Vilardell
Journal:  J Endocrinol Invest       Date:  1987-12       Impact factor: 4.256

Review 8.  Cushing syndrome: current concepts of diagnosis and therapy.

Authors:  D M Cook; J W Kendall; R Jordan
Journal:  West J Med       Date:  1980-02
  8 in total

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