Literature DB >> 18522825

PPARdelta/beta: the lobbyist switching macrophage allegiance in favor of metabolism.

Béatrice Desvergne1.   

Abstract

Macrophages, which belong to the immune system, are increasingly being recognized for their contribution to metabolic regulation. In two studies by Kang et al. (2008) and Odegaard et al. (2008) in this issue of Cell Metabolism, we learn that alternative activation (M2a) of resident macrophages in liver and adipose tissue depends highly on PPARdelta/beta activity, leading to improved fatty acid metabolism and insulin sensitivity.

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Year:  2008        PMID: 18522825     DOI: 10.1016/j.cmet.2008.05.002

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  12 in total

1.  Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation.

Authors:  Jisu Oh; Amy E Riek; Sherry Weng; Marvin Petty; David Kim; Marco Colonna; Marina Cella; Carlos Bernal-Mizrachi
Journal:  J Biol Chem       Date:  2012-02-22       Impact factor: 5.157

Review 2.  Peroxisome proliferator-activated receptors, metabolic syndrome and cardiovascular disease.

Authors:  Salman Azhar
Journal:  Future Cardiol       Date:  2010-09

3.  Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses.

Authors:  Yang Wang; Akram A Da'Dara; Paul G Thomas; Donald A Harn
Journal:  Immunology       Date:  2009-11-16       Impact factor: 7.397

4.  Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.

Authors:  Guadalupe Sabio; Norman J Kennedy; Julie Cavanagh-Kyros; Dae Young Jung; Hwi Jin Ko; Helena Ong; Tamera Barrett; Jason K Kim; Roger J Davis
Journal:  Mol Cell Biol       Date:  2010-01       Impact factor: 4.272

5.  TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.

Authors:  R Tomasini; V Secq; L Pouyet; A K Thakur; M Wilhelm; J Nigri; S Vasseur; P Berthezene; E Calvo; G Melino; T W Mak; J L Iovanna
Journal:  Cell Death Differ       Date:  2012-09-14       Impact factor: 15.828

6.  Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice.

Authors:  Michaela C Stanton; Shu-Cheng Chen; James V Jackson; Alberto Rojas-Triana; David Kinsley; Long Cui; Jay S Fine; Scott Greenfeder; Loretta A Bober; Chung-Her Jenh
Journal:  J Inflamm (Lond)       Date:  2011-03-16       Impact factor: 4.981

7.  Bone marrow p16INK4a-deficiency does not modulate obesity, glucose homeostasis or atherosclerosis development.

Authors:  Kristiaan Wouters; Céline Cudejko; Marion J J Gijbels; Lucia Fuentes; Kadiombo Bantubungi; Jonathan Vanhoutte; Rebecca Dièvart; Charlotte Paquet; Emmanuel Bouchaert; Sarah Anissa Hannou; Florence Gizard; Anne Tailleux; Menno P J de Winther; Bart Staels; Réjane Paumelle
Journal:  PLoS One       Date:  2012-03-05       Impact factor: 3.240

Review 8.  Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function.

Authors:  Greta M P Giordano Attianese; Béatrice Desvergne
Journal:  Nucl Recept Signal       Date:  2015-04-27

9.  Human resistin and the RELM of Inflammation in diabesity.

Authors:  Fatima Al Hannan; Kevin Gerard Culligan
Journal:  Diabetol Metab Syndr       Date:  2015-06-18       Impact factor: 3.320

Review 10.  Macrophage polarization in obesity and type 2 diabetes: weighing down our understanding of macrophage function?

Authors:  Michael James Kraakman; Andrew James Murphy; Karin Jandeleit-Dahm; Hélène L Kammoun
Journal:  Front Immunol       Date:  2014-09-26       Impact factor: 7.561

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