Literature DB >> 18522718

Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report.

Felix Gundling1, Henning Wittenburg, Andrea Tannapfel, Joachim Mossner.   

Abstract

INTRODUCTION: Whipple's disease is a rare systemic infectious disorder caused by Tropheryma whipplei. CASE
PRESENTATION: We report a 68-year-old male with Whipple's disease of the central nervous system following long-term antibiotic therapy and many years after the initial clinical onset.
CONCLUSION: The combination of trimethoprim and sulphamethoxazole does not prevent or cure involvement of the central nervous system in all patients with Whipple's disease. If relapse of the central nervous system occurs treatment with meropenem might be a useful alternative.

Entities:  

Year:  2008        PMID： 18522718      PMCID： PMC2443157          DOI： 10.1186/1752-1947-2-191

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN： 1752-1947


  15 in total

1.  Neurology of Whipple's disease.

Authors:  M Anderson
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-01       Impact factor: 10.154

Review 2.  Whipple's disease and "Tropheryma whippelii".

Authors:  F Dutly; M Altwegg
Journal:  Clin Microbiol Rev       Date:  2001-07       Impact factor: 26.132

Review 3.  Neurologic presentation of Whipple disease: report of 12 cases and review of the literature.

Authors:  Antoine Gerard; Françoise Sarrot-Reynauld; Eric Liozon; Pascal Cathebras; Gerard Besson; Christophe Robin; Alain Vighetto; Jean-François Mosnier; Isabelle Durieu; Denis Vital Durand; Hugues Rousset
Journal:  Medicine (Baltimore)       Date:  2002-11       Impact factor: 1.889

Review 4.  Whipple disease of the central nervous system.

Authors:  W Michael Scheld
Journal:  J Infect Dis       Date:  2003-09-09       Impact factor: 5.226

5.  Immunosuppressive therapy in Whipple's disease patients is associated with the appearance of gastrointestinal manifestations.

Authors:  René Mahnel; Anja Kalt; Sabine Ring; Andreas Stallmach; Warren Strober; Thomas Marth
Journal:  Am J Gastroenterol       Date:  2005-05       Impact factor: 10.864

6.  Oculo-facial-skeletal myorhythmia in Whipple disease: treatment with ceftriaxone.

Authors:  C H Adler; S L Galetta
Journal:  Ann Intern Med       Date:  1990-03-15       Impact factor: 25.391

7.  Treatment of refractory Whipple disease with interferon-gamma.

Authors:  T Schneider; A Stallmach; A von Herbay; T Marth; W Strober; M Zeitz
Journal:  Ann Intern Med       Date:  1998-12-01       Impact factor: 25.391

8.  [Whipple disease and non-Hodgkin lymphoma].

Authors:  U Gruner; P Goesch; A Donner; U Peters
Journal:  Z Gastroenterol       Date:  2001-04       Impact factor: 2.000

9.  Reduced peripheral and mucosal Tropheryma whipplei-specific Th1 response in patients with Whipple's disease.

Authors:  Verena Moos; Désirée Kunkel; Thomas Marth; Gerhard E Feurle; Bernard LaScola; Ralf Ignatius; Martin Zeitz; Thomas Schneider
Journal:  J Immunol       Date:  2006-08-01       Impact factor: 5.422

Review 10.  Whipple's disease.

Authors:  Thomas Marth; Didier Raoult
Journal:  Lancet       Date:  2003-01-18       Impact factor: 79.321
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