PURPOSE: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. PATIENTS AND METHODS: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. RESULTS: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. DISCUSSION: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches.
PURPOSE: Periosteal osteosarcomas are rare cartilage-rich bone tumours characterized by a juxtacortical eccentric position and are normally regarded oncologically as of intermediate to high grade.Their low incidence is mirrored by a small number of reported cases in the world literature. While there is general agreement that wide surgical excision is required, there is a paucity of evidence regarding adjuvant therapy. Previous reports have not indicated any consistent approach to this to allow appraisal. PATIENTS AND METHODS: We report 17 cases treated at our centre over 16 years. Our policy was to use chemotherapy when the tumour showed any features of high grade. RESULTS: To date, no deaths have resulted from recurrence or metastasis of the tumour although there have been two deaths from other causes. DISCUSSION: Comparison of survival with existing studies is made to draw conclusions regarding future treatment of this condition in terms of surgical and adjuvant approaches.
Authors: V H Bramwell; M Burgers; R Sneath; R Souhami; A T van Oosterom; P A Voûte; J Rouesse; D Spooner; A W Craft; R Somers Journal: J Clin Oncol Date: 1992-10 Impact factor: 44.544
Authors: Aditya V Maheshwari; James S Jelinek; Nita L Seibel; Aurelia M Meloni-Ehrig; Dhruv Kumar; Robert M Henshaw Journal: Skeletal Radiol Date: 2012-02-17 Impact factor: 2.199