Literature DB >> 18521292

Conformal radiotherapy facilitates the delivery of concurrent chemotherapy and radiotherapy: a case of primitive neuroectodermal tumour of the chest wall.

C E Coles1, N Twyman, H M Earl, N G Burnet.   

Abstract

We illustrate the principle of conformal radiotherapy by discussing the case of a patient with a primitive neuroectodermal tumour of the chest wall. Recent advances in radiotherapy planning enable precise localization of the planning target volume (PTV) and normal organs at risk of irradiation. Customized blocks are subsequently designed to produce a treatment field that 'conforms' to the PTV. The use of conformal radiotherapy (CRT) in this case facilitated the delivery of concurrent chemotherapy and radiotherapy by significantly reducing the volume of red marrow irradiated.The lack of acute and late toxicities was attributed to optimal exclusion of normal tissues from the treatment field, made possible by CRT.

Entities:  

Year:  2000        PMID: 18521292      PMCID: PMC2395438          DOI: 10.1080/13577140020008101

Source DB:  PubMed          Journal:  Sarcoma        ISSN: 1357-714X


  7 in total

1.  Radiotherapy in Ewing's sarcoma and PNET of the chest wall: results of the trials CESS 81, CESS 86 and EICESS 92.

Authors:  A Schuck; J Hofmann; C Rübe; A Hillmann; S Ahrens; M Paulussen; H Jürgens; J Dunst; N Willich
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-12-01       Impact factor: 7.038

2.  The significance of anemia in clinical radiation therapy.

Authors:  R S Bush
Journal:  Int J Radiat Oncol Biol Phys       Date:  1986-11       Impact factor: 7.038

3.  Value of conformal planning in the radiotherapy of soft tissue sarcoma.

Authors:  M H Robinson; A M Bidmead; C L Harmer
Journal:  Clin Oncol (R Coll Radiol)       Date:  1992-09       Impact factor: 4.126

4.  Comparison of radiation side-effects of conformal and conventional radiotherapy in prostate cancer: a randomised trial.

Authors:  D P Dearnaley; V S Khoo; A R Norman; L Meyer; A Nahum; D Tait; J Yarnold; A Horwich
Journal:  Lancet       Date:  1999-01-23       Impact factor: 79.321

5.  Radiation therapy in Ewing's sarcoma: an update of the CESS 86 trial.

Authors:  J Dunst; H Jürgens; R Sauer; H Pape; M Paulussen; W Winkelmann; C Rübe
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-07-15       Impact factor: 7.038

6.  Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study.

Authors:  A Craft; S Cotterill; A Malcolm; D Spooner; R Grimer; R Souhami; J Imeson; I Lewis
Journal:  J Clin Oncol       Date:  1998-11       Impact factor: 44.544

7.  The Impact of Radiotherapy Dose on Local Control of Ewing's Sarcoma of Bone.

Authors:  N G Burnet; J M Bliss; C L Harmer
Journal:  Sarcoma       Date:  1997
  7 in total
  1 in total

Review 1.  Techniques to modulate radiotherapy toxicity and outcome in soft tissue sarcoma.

Authors:  Brian O'Sullivan; Iain Ward; Tara Haycocks; Michael Sharpe
Journal:  Curr Treat Options Oncol       Date:  2003-12
  1 in total

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