Literature DB >> 18520807

Prevalence of brain metastases immediately before prophylactic cranial irradiation in limited disease small cell lung cancer patients with complete remission to chemoradiotherapy: a single institution experience.

Farkhat Manapov1, Gunther Klautke, Rainer Fietkau.   

Abstract

This single-center study investigated the prevalence of brain metastases immediately before prophylactic cranial irradiation in 40 consecutive limited disease small cell lung cancer complete responders to chemoradiotherapy and revealed that 13/40 (32.5%; 95% confidence interval: 18-47%) patients suffer relapse with brain metastases and show a significantly worse prognosis than those without detected brain metastases.

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Year:  2008        PMID： 18520807     DOI： 10.1097/JTO.0b013e3181757a76

Source DB:  PubMed          Journal:  J Thorac Oncol        ISSN： 1556-0864            Impact factor:   15.609


  21 in total

1.  Frequency of Silent Brain Metastasis Before Prophylactic Cranial Irradiation in Small Cell Lung Cancer.

Authors:  Ufuk Yılmaz; Esra Korkmaz Kırakli; Ümit Gürlek; Yasemin Özdoğan; Bahri Gümüş; Salih Akşit
Journal:  Turk Thorac J       Date:  2017-01-01

2.  Prognostic role of patient gender in limited-disease small-cell lung cancer treated with chemoradiotherapy.

Authors:  Olarn Roengvoraphoj; Chukwuka Eze; Maximilian Niyazi; Minglun Li; Guido Hildebrandt; Rainer Fietkau; Claus Belka; Farkhad Manapov
Journal:  Strahlenther Onkol       Date:  2016-11-16       Impact factor: 3.621

3.  Chemoradiotherapy duration correlates with overall survival in limited disease SCLC patients with poor initial performance status who successfully completed multimodality treatment.

Authors:  F Manapov; S Klöcking; M Niyazi; C Belka; G Hildebrandt; R Fietkau; G Klautke
Journal:  Strahlenther Onkol       Date:  2011-12-23       Impact factor: 3.621

4.  Primary tumor response to chemoradiotherapy in limited-disease small-cell lung cancer correlates with duration of brain-metastasis free survival.

Authors:  Farkhad Manapov; Sabine Klöcking; Maximilian Niyazi; Victor Levitskiy; Claus Belka; Guido Hildebrandt; Rainer Fietkau; Gunther Klautke
Journal:  J Neurooncol       Date:  2012-05-20       Impact factor: 4.130

5.  Central nervous system relapse continues to be a therapeutic challenge in extensive disease small-cell lung cancer patients with initial symptomatic brain metastases and good response to chemoradiotherapy.

Authors:  Farkhad Manapov
Journal:  J Neurooncol       Date:  2009-12-15       Impact factor: 4.130

6.  Management of brain metastasis with magnetic resonance imaging and stereotactic irradiation attenuated benefits of prophylactic cranial irradiation in patients with limited-stage small cell lung cancer.

Authors:  Yuichi Ozawa; Minako Omae; Masato Fujii; Takashi Matsui; Masato Kato; Shinya Sagisaka; Kazuhiro Asada; Masato Karayama; Toshihiro Shirai; Kazumasa Yasuda; Yutaro Nakamura; Naoki Inui; Kazunari Yamada; Koshi Yokomura; Takafumi Suda
Journal:  BMC Cancer       Date:  2015-08-15       Impact factor: 4.430

7.  Investigating a Correlation between Chemoradiotherapy Schedule Parameters and Overall Survival in a real-life LD SCLC Patient Cohort.

Authors:  Farkhad Manapov; Chukwuka Eze; Maximilian Niyazi; Olarn Roengvoraphoj; Minglun Li; Nina-Sophie Hegemann; Guido Hildebrandt; Rainer Fietkau; Claus Belka
Journal:  J Cancer       Date:  2016-10-17       Impact factor: 4.207

8.  Risk factors for brain metastases after prophylactic cranial irradiation in small cell lung cancer.

Authors:  Haiyan Zeng; Peng Xie; Xue Meng; Shuanghu Yuan; Xindong Sun; Wanlong Li; Bingjie Fan; Xiaolin Li; Jinming Yu
Journal:  Sci Rep       Date:  2017-02-16       Impact factor: 4.379

9.  Efficacy of prophylactic cranial irradiation in patients with limited-disease small-cell lung cancer who were confirmed to have no brain metastasis via magnetic resonance imaging after initial chemoradiotherapy.

Authors:  Nobuaki Mamesaya; Kazushige Wakuda; Katsuhiro Omae; Eriko Miyawaki; Mie Kotake; Takumi Fujiwara; Takahisa Kawamura; Haruki Kobayashi; Kazuhisa Nakashima; Shota Omori; Akira Ono; Hirotsugu Kenmotsu; Tateaki Naito; Haruyasu Murakami; Keita Mori; Hideyuki Harada; Masahiro Endo; Takashi Nakajima; Toshiaki Takahashi
Journal:  Oncotarget       Date:  2018-04-03

Review 10.  Strategies to Preserve Cognition in Patients With Brain Metastases: A Review.

Authors:  Tyler P Robin; Chad G Rusthoven
Journal:  Front Oncol       Date:  2018-10-09       Impact factor: 6.244
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