Literature DB >> 18520038

Anti-candida activity of sodium sulfite.

Ayako Ogasawara1, Yuki Iino, Keio Sato, Yuta Nakajima, Satoko Bessho, Toshihiko Watanabe, Takeshi Mikami, Tatsuji Matsumoto.   

Abstract

The growth of Candida albicans in RPMI1640 medium was inhibited by sodium sulfite between pH 3-6. Under the condition of pH 7, growth of C. albicans was not inhibited by sodium sulfite. Under an acidic pH condition, sodium sulfite had a candidacidal effect and the activity was expressed within 150 min. The concentration of ATP in C. albicans was decreased by sodium sulfite. Ethanol production by C. albicans was inhibited by sodium sulfite at pH 5. These results indicated that the candidacidal effect of sodium sulfite under acidic conditions was caused by interruption of alcohol fermentation and aerobic respiration.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18520038     DOI： 10.1248/bpb.31.1101

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN： 0918-6158            Impact factor:   2.233


  3 in total

1.  Expanding the Limits of Thermoacidophily in the Archaeon Sulfolobus solfataricus by Adaptive Evolution.

Authors:  Samuel McCarthy; Tyler Johnson; Benjamin J Pavlik; Sophie Payne; Wendy Schackwitz; Joel Martin; Anna Lipzen; Erica Keffeler; Paul Blum
Journal:  Appl Environ Microbiol       Date:  2015-11-20       Impact factor: 4.792

2.  Adaptation of Candida albicans to Reactive Sulfur Species.

Authors:  Yasmin Chebaro; Michael Lorenz; Alice Fa; Rui Zheng; Michael Gustin
Journal:  Genetics       Date:  2017-02-24       Impact factor: 4.562

3.  Combining Genome-Wide Gene Expression Analysis (RNA-seq) and a Gene Editing Platform (CRISPR-Cas9) to Uncover the Selectively Pro-oxidant Activity of Aurone Compounds Against Candida albicans.

Authors:  Fatmah M Alqahtani; Scott T Handy; Caleb L Sutton; Mary B Farone
Journal:  Front Microbiol       Date:  2021-07-15       Impact factor: 5.640
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.