Literature DB >> 18518252

Analysis of DNA elasticity.

R P Linna1, K Kaski.   

Abstract

With a model that incorporates hydrodynamics directly, we show that flow experiments can be used for detecting some characteristics of the DNA elasticity which manifest themselves clearly at large length scales but cannot be observed by mechanical forcing experiments even at very small length scales. By systematic analysis, the conclusiveness of different experimental methods is evaluated. For the wormlike chain, confirmed as the correct model for DNA, we find an underlying scaling relation between its extension and flow velocity of the form L(p) approximately v(0.155), which emphasizes the significance of hydrodynamics.

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Year:  2008        PMID: 18518252     DOI: 10.1103/PhysRevLett.100.168104

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  2 in total

1.  Microscopic mechanism for experimentally observed anomalous elasticity of DNA in two dimensions.

Authors:  Nicolas Destainville; Manoel Manghi; John Palmeri
Journal:  Biophys J       Date:  2009-06-03       Impact factor: 4.033

2.  Atomic force microscopy study of DNA flexibility on short length scales: smooth bending versus kinking.

Authors:  Alexey K Mazur; Mounir Maaloum
Journal:  Nucleic Acids Res       Date:  2014-11-20       Impact factor: 16.971

  2 in total

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