Literature DB >> 1851810

The inhibitory effects of oligonucleotides, complementary to Marek's disease virus mRNA transcribed from the BamHI-H region, on the proliferation of transformed lymphoblastoid cells, MDCC-MSB1.

M Kawamura1, M Hayashi, T Furuichi, M Nonoyama, E Isogai, S Namioka.   

Abstract

An oligonucleotide complementary to the splice donor sequence of the 1.8 kb gene family produced from the BamHI-H region of Marek's disease virus (MDV) DNA inhibited the proliferation of the MDV-derived lymphoblastoid cell line, MDCC-MSB1 (MSB-1), but not that of the avian lymphoid leukosis-derived lymphoblastoid cell line, LSCC-BK3. Colony formation in soft agar was also inhibited by treatment of MSB-1 cells with the antisense oligonucleotide. It is hypothesized that expression of the 1.8 kb gene family produced from the BamHI-H region is directly associated with the maintenance of the tumorigenic state of transformed Marek's disease-derived lymphoblastoid cells.

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Year:  1991        PMID： 1851810     DOI： 10.1099/0022-1317-72-5-1105

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  16 in total

1.  The genome of a very virulent Marek's disease virus.

Authors:  E R Tulman; C L Afonso; Z Lu; L Zsak; D L Rock; G F Kutish
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

2.  Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.

Authors:  Lucy F Lee; Xiaoping Cui; Zhizhong Cui; Isabel Gimeno; Blanca Lupiani; Sanjay M Reddy
Journal:  Virus Genes       Date:  2005-08       Impact factor: 2.332

3.  Isolation and characterization of cDNAs from BamHI-H gene family RNAs associated with the tumorigenicity of Marek's disease virus.

Authors:  F Peng; G Bradley; A Tanaka; G Lancz; M Nonoyama
Journal:  J Virol       Date:  1992-12       Impact factor: 5.103

4.  Recombinant Marek's disease virus (MDV)-derived lymphoblastoid cell lines: regulation of a marker gene within the context of the MDV genome.

Authors:  M S Parcells; R L Dienglewicz; A S Anderson; R W Morgan
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

5.  Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line.

Authors:  E Le Rouzic; B Perbal
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

6.  Transactivation activity of Meq, a Marek's disease herpesvirus bZIP protein persistently expressed in latently infected transformed T cells.

Authors:  Z Qian; P Brunovskis; F Rauscher; L Lee; H J Kung
Journal:  J Virol       Date:  1995-07       Impact factor: 5.103

7.  Identification of an immediate-early gene in the Marek's disease virus long internal repeat region which encodes a unique 14-kilodalton polypeptide.

Authors:  Y Hong; P M Coussens
Journal:  J Virol       Date:  1994-06       Impact factor: 5.103

8.  Alterations of the MDV oncogenic regions in an MDV transformed lymphoblastoid cell line.

Authors:  E Le Rouzic; P Thoraval; M Afanassieff; Y Cherel; G Dambrine; B Perbal
Journal:  Mol Pathol       Date:  2002-08

9.  Structural analysis and transcriptional mapping of the Marek's disease virus gene encoding pp38, an antigen associated with transformed cells.

Authors:  Z Z Cui; L F Lee; J L Liu; H J Kung
Journal:  J Virol       Date:  1991-12       Impact factor: 5.103

10.  Status of Marek's disease virus in established lymphoma cell lines: herpesvirus integration is common.

Authors:  H J Delecluse; W Hammerschmidt
Journal:  J Virol       Date:  1993-01       Impact factor: 5.103
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