Literature DB >> 18517319

Conformation and trapping rate of DNA at a convergent stagnation point.

Jennifer Kreft1, Yeng-Long Chen, Hsueh-Chia Chang.   

Abstract

We use a lattice-Boltzmann based Brownian dynamics simulation to investigate the elongation of DNA at a convergent stagnation point trapped by a uniform attractive potential. The trapping rate of the DNA is not sensitive to the potential and, consistent with a mean field theory, scales as the Peclet number, Pe(1/3) . Surprisingly, we find that the coiled state is favored over the stretched state at high Pe. The final elongation is determined by conformation changes during transport to the stagnation point, rather than hydrodynamic stretching at that point.

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Year:  2008        PMID: 18517319     DOI: 10.1103/PhysRevE.77.030801

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  2 in total

1.  Separation of DNA by length in rotational flow: Lattice-Boltzmann-based simulations.

Authors:  Faihan Alfahani; Michael Antonelli; Jennifer Kreft Pearce
Journal:  Biomicrofluidics       Date:  2015-07-27       Impact factor: 2.800

Review 2.  Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces.

Authors:  Ramanathan Vaidyanathan; Shuvashis Dey; Laura G Carrascosa; Muhammad J A Shiddiky; Matt Trau
Journal:  Biomicrofluidics       Date:  2015-12-08       Impact factor: 2.800

  2 in total

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