| Literature DB >> 18516058 |
Abstract
The unpredictable progression of IgA nephropathy hinders its treatment. The correlation of renal dysfunction with the immunophenotype of leukocytic infiltrates revealed interstitial CD20(+) cells and tubular NKG7(+)(GMP-17(+))/CD8(+) intraepithelial cells as predictive markers of progression in early-phase IgA nephropathy. This suggests that adaptive and innate immune responses mediate progression.Entities:
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Year: 2008 PMID： 18516058 DOI： 10.1038/ki.2008.158
Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612