Literature DB >> 18514273

Complications of epilepsy surgery in the first 8 years after neurosurgical training.

A Chris Heller1, Rachelle V Padilla, Adam N Mamelak.   

Abstract

BACKGROUND: Surgery is the most effective means of eliminating or reducing seizures in cases of medically refractory epilepsy. As elective surgery, however, there is little tolerance for complications. We have reviewed the early operative experience of a single epilepsy surgeon to identify the presence or absence of a surgical learning curve.
METHODS: All phase II (diagnostic) and phase III (therapeutic) procedures for epilepsy surgery during the surgeon's first 8 years of practice were retrospectively reviewed. Complications were analyzed and subdivided into major or minor. Trends in complication rates were evaluated.
RESULTS: During the first 8 years, there were 96 phase II and 94 phase III cases. Complications occurred in 26 (14%) of 190 cases, including 16 major (8%) and 10 minor (5%) complications. There was a decline in both the number and severity of complications associated with temporal lobectomy over time. Complications involving subdural grids shifted, over time, from those attributed to surgical technique or experience to those felt to be unavoidable risks of the procedure itself. Over time there was a decline in the proportion of major vs minor complications, but the overall complication rate remained stable.
CONCLUSIONS: There appears to be a surgical learning curve for epilepsy surgery involving complications associated with removal of medial temporal lobe structures, which lessen as the surgeon's experience increases.

Entities:  

Mesh:

Year:  2008        PMID: 18514273     DOI: 10.1016/j.surneu.2008.03.023

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  5 in total

1.  Improved outcomes in pediatric epilepsy surgery: the UCLA experience, 1986-2008.

Authors:  M Hemb; T R Velasco; M S Parnes; J Y Wu; J T Lerner; J H Matsumoto; S Yudovin; W D Shields; R Sankar; N Salamon; H V Vinters; G W Mathern
Journal:  Neurology       Date:  2010-04-28       Impact factor: 9.910

2.  Comparison of the real-world effectiveness of vertical versus lateral functional hemispherotomy techniques for pediatric drug-resistant epilepsy: A post hoc analysis of the HOPS study.

Authors:  Aria Fallah; Evan Lewis; George M Ibrahim; Olivia Kola; Chi-Hong Tseng; William B Harris; Jia-Shu Chen; Kao-Min Lin; Li-Xin Cai; Qing-Zhu Liu; Jiu-Luan Lin; Wen-Jing Zhou; Gary W Mathern; Matthew D Smyth; Brent R O'Neill; Roy W R Dudley; John Ragheb; Sanjiv Bhatia; Daniel Delev; Georgia Ramantani; Josef Zentner; Anthony C Wang; Christian Dorfer; Martha Feucht; Thomas Czech; Robert J Bollo; Galymzhan Issabekov; Hongwei Zhu; Mary Connolly; Paul Steinbok; Jian-Guo Zhang; Kai Zhang; Eveline Teresa Hidalgo; Howard L Weiner; Lily Wong-Kisiel; Samuel Lapalme-Remis; Manjari Tripathi; Poodipedi Sarat Chandra; Walter Hader; Feng-Peng Wang; Yi Yao; Pierre-Olivier Champagne; Tristan Brunette-Clément; Qiang Guo; Shao-Chun Li; Marcelo Budke; Maria Angeles Pérez-Jiménez; Christian Raftopoulos; Patrice Finet; Pauline Michel; Karl Schaller; Martin N Stienen; Valentina Baro; Christian Cantillano Malone; Juan Pociecha; Noelia Chamorro; Valeria L Muro; Marec von Lehe; Silvia Vieker; Chima Oluigbo; William D Gaillard; Mashael Al-Khateeb; Faisal Al Otaibi; Niklaus Krayenbühl; Jeffrey Bolton; Phillip L Pearl; Alexander G Weil
Journal:  Epilepsia       Date:  2021-09-12       Impact factor: 6.740

Review 3.  Embryonic stem cell-derived neural precursor grafts for treatment of temporal lobe epilepsy.

Authors:  Xu Maisano; Joseph Carpentino; Sandy Becker; Robert Lanza; Gloster Aaron; Laura Grabel; Janice R Naegele
Journal:  Neurotherapeutics       Date:  2009-04       Impact factor: 7.620

Review 4.  Temporal lobe resective surgery for medically intractable epilepsy: a review of complications and side effects.

Authors:  Iordanis Georgiadis; Effie Z Kapsalaki; Kostas N Fountas
Journal:  Epilepsy Res Treat       Date:  2013-10-31

5.  Human fetal brain-derived neural stem/progenitor cells grafted into the adult epileptic brain restrain seizures in rat models of temporal lobe epilepsy.

Authors:  Haejin Lee; Seokhwan Yun; Il-Sun Kim; Il-Shin Lee; Jeong Eun Shin; Soo Chul Park; Won-Joo Kim; Kook In Park
Journal:  PLoS One       Date:  2014-08-08       Impact factor: 3.240

  5 in total

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