Literature DB >> 18513965

5-Substituted isophthalamides as insulin receptor sensitizers.

Louise Robinson1, Sonia Bajjalieh, Nicholas Cairns, Robert T Lum, Robert W Macsata, Vara Prasad Manchem, Sophia J Park, Sandhya Rao, Steven R Schow, Songyuan Shi, Wayne R Spevak.   

Abstract

A novel series of 5-substituted isophthalamides and their structure-activity relationship as insulin receptor sensitizers is discussed.

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Year:  2008        PMID： 18513965     DOI： 10.1016/j.bmcl.2008.05.031

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  2 in total

1.  Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator.

Authors:  Margaret Wu; Ge Dai; Jun Yao; Scott Hoyt; Liangsu Wang; James Mu
Journal:  PLoS One       Date:  2015-03-23       Impact factor: 3.240

Review 2.  The Insulin Receptor: An Important Target for the Development of Novel Medicines and Pesticides.

Authors:  Xiaohong Zhang; Xuezhen Zhu; Xiaoyang Bi; Jiguang Huang; Lijuan Zhou
Journal:  Int J Mol Sci       Date:  2022-07-14       Impact factor: 6.208
  2 in total

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