| Literature DB >> 18513860 |
Bavo De Witte1, Jo Dewulf, Kristof Demeestere, Herman Van Langenhove.
Abstract
A bubble reactor was used for ozonation of the antibiotic ciprofloxacin. Effects of process parameters ozone inlet concentration, ciprofloxacin concentration, temperature, pH and H(2)O(2) concentration were tested. Desethylene ciprofloxacin was identified, based on HPLC-MS analysis, as one of the degradation products. Formation of desethylene ciprofloxacin was highly dependent on pH, with the highest concentration measured at pH 10. Radical scavengers t-butanol and parachlorobenzoic acid were added in order to gain mechanistic understanding. Radical species other than hydroxyl radicals were suggested to occur at acidic pH which can explain fast ciprofloxacin ozonation at pH 3.Entities:
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Year: 2008 PMID： 18513860 DOI： 10.1016/j.jhazmat.2008.04.021
Source DB: PubMed Journal: J Hazard Mater ISSN： 0304-3894 Impact factor: 10.588