Literature DB >> 18512929

Mild, efficient Friedel-Crafts acylations from carboxylic acids using cyanuric chloride and AlCl3.

Cyrous O Kangani1, Billy W Day.   

Abstract

A mild method for Friedel-Crafts acylation with aromatic and aliphatic carboxylic acids using cyanuric chloride, pyridine, and AlCl(3) was developed. Both inter- and intramolecular acylations were achieved at room temperature in high yield and in very short reaction times.

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Year:  2008        PMID: 18512929     DOI: 10.1021/ol800752v

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Total synthesis and absolute stereochemical assignment of kibdelone C.

Authors:  David L Sloman; Jeffrey W Bacon; John A Porco
Journal:  J Am Chem Soc       Date:  2011-06-15       Impact factor: 15.419

2.  Rational Engineered C-Acyltransferase Transforms Sterically Demanding Acyl Donors.

Authors:  Anna Żądło-Dobrowolska; Lucas Hammerer; Tea Pavkov-Keller; Karl Gruber; Wolfgang Kroutil
Journal:  ACS Catal       Date:  2019-12-27       Impact factor: 13.084

3.  Mild and efficient cyanuric chloride catalyzed Pictet-Spengler reaction.

Authors:  Ashish Sharma; Mrityunjay Singh; Nitya Nand Rai; Devesh Sawant
Journal:  Beilstein J Org Chem       Date:  2013-06-26       Impact factor: 2.883

4.  Efficient TCT-catalyzed synthesis of 1,5-benzodiazepine derivatives under mild conditions.

Authors:  Chun-Wei Kuo; Chun-Chao Wang; Veerababurao Kavala; Ching-Fa Yao
Journal:  Molecules       Date:  2008-09-25       Impact factor: 4.411

  4 in total

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