Literature DB >> 18511623

Systematic reviews of empirical bioethics.

D Strech1, M Synofzik, G Marckmann.   

Abstract

BACKGROUND: Publications and discussions of survey research in empirical bioethics have steadily increased over the past two decades. However, findings often differ among studies with similar research questions. As a consequence, ethical reasoning that considers only parts of the existing literature and does not apply systematic reviews tends to be biased. To date, we lack a systematic review (SR) methodology that takes into account the specific conceptual and practical challenges of empirical bioethics.
METHODS: The steps of systematically reviewing empirical findings in bioethics are presented and critically discussed. In particular, (a) the limitations of traditional SR methodologies in the field of empirical bioethics are critically discussed, and (b) conceptual and practical recommendations for SRs in empirical bioethics that are (c) based on the authors' review experiences in healthcare ethics are presented.
RESULTS: A 7-step approach for SRs of empirical bioethics is proposed: (1) careful definition of review question; (2) selection of relevant databases; (3) application of ancillary search strategies; (4) development of search algorithms; (5) relevance assessment of the retrieved references; (6) quality assessment of included studies; and (7) data analysis and presentation. Conceptual and practical challenges arise because of various peculiarities in reviewing empirical bioethics literature and can lead to biased results if they are not taken into account.
CONCLUSIONS: If suitably adapted to the peculiarities of the field, SRs of empirical bioethics provide transparent information for ethical reasoning and decision-making that is less biased than single studies.

Entities:  

Mesh:

Year:  2008        PMID: 18511623     DOI: 10.1136/jme.2007.021709

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  22 in total

Review 1.  A systematic review of the empirical literature evaluating IRBs: what we know and what we still need to learn.

Authors:  Lura Abbott; Christine Grady
Journal:  J Empir Res Hum Res Ethics       Date:  2011-03       Impact factor: 1.742

2.  Ethical, Legal, and Social Implications of Symptom Checker Apps in Primary Health Care (CHECK.APP): Protocol for an Interdisciplinary Mixed Methods Study.

Authors:  Anna-Jasmin Wetzel; Roland Koch; Christine Preiser; Regina Müller; Malte Klemmt; Robert Ranisch; Hans-Jörg Ehni; Urban Wiesing; Monika A Rieger; Tanja Henking; Stefanie Joos
Journal:  JMIR Res Protoc       Date:  2022-05-16

Review 3.  Are physicians willing to ration health care? Conflicting findings in a systematic review of survey research.

Authors:  Daniel Strech; Govind Persad; Georg Marckmann; Marion Danis
Journal:  Health Policy       Date:  2008-12-13       Impact factor: 2.980

4.  Reasons Why Post-Trial Access to Trial Drugs Should, or Need not be Ensured to Research Participants: A Systematic Review.

Authors:  Neema Sofaer; Daniel Strech
Journal:  Public Health Ethics       Date:  2011-07-11       Impact factor: 1.940

5.  How to write a systematic review of reasons.

Authors:  Daniel Strech; Neema Sofaer
Journal:  J Med Ethics       Date:  2011-11-11       Impact factor: 2.903

6.  Did we describe what you meant? Findings and methodological discussion of an empirical validation study for a systematic review of reasons.

Authors:  Marcel Mertz; Neema Sofaer; Daniel Strech
Journal:  BMC Med Ethics       Date:  2014-09-27       Impact factor: 2.652

7.  Evidence-based ethics--what it should be and what it shouldn't.

Authors:  Daniel Strech
Journal:  BMC Med Ethics       Date:  2008-10-20       Impact factor: 2.652

Review 8.  Balancing costs and benefits at different stages of medical innovation: a systematic review of Multi-criteria decision analysis (MCDA).

Authors:  Philip Wahlster; Mireille Goetghebeur; Christine Kriza; Charlotte Niederländer; Peter Kolominsky-Rabas
Journal:  BMC Health Serv Res       Date:  2015-07-09       Impact factor: 2.655

9.  Research across the disciplines: a road map for quality criteria in empirical ethics research.

Authors:  Marcel Mertz; Julia Inthorn; Günter Renz; Lillian Geza Rothenberger; Sabine Salloch; Jan Schildmann; Sabine Wöhlke; Silke Schicktanz
Journal:  BMC Med Ethics       Date:  2014-03-01       Impact factor: 2.652

Review 10.  The ethical issues regarding consent to clinical trials with pre-term or sick neonates: a systematic review (framework synthesis) of the empirical research.

Authors:  E Wilman; C Megone; S Oliver; L Duley; G Gyte; J M Wright
Journal:  Trials       Date:  2015-11-04       Impact factor: 2.279

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