Literature DB >> 18511323

Cerebellar ataxia following prolonged use of metronidazole: case report and literature review.

Kalpeshkumar Patel1, Israel Green-Hopkins, Stanley Lu, Allan R Tunkel.   

Abstract

Cerebellar toxicity is a rare adverse event in patients treated with metronidazole. Here, we present a patient who developed cerebellar toxicity accompanied by objective abnormalities on magnetic resonance imaging, and review the literature on this unusual reaction. Discontinuation of metronidazole almost always results in resolution of symptoms and structural lesions.

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Year:  2008        PMID: 18511323     DOI: 10.1016/j.ijid.2008.03.006

Source DB:  PubMed          Journal:  Int J Infect Dis        ISSN: 1201-9712            Impact factor:   3.623


  23 in total

Review 1.  Drug-induced cerebellar ataxia: a systematic review.

Authors:  J van Gaalen; F G Kerstens; R P P W M Maas; L Härmark; B P C van de Warrenburg
Journal:  CNS Drugs       Date:  2014-12       Impact factor: 5.749

2.  Metronidazole-induced encephalopathy: a systematic review.

Authors:  Caspar Godthaab Sørensen; William Kristian Karlsson; Faisal Mohammad Amin; Mette Lindelof
Journal:  J Neurol       Date:  2018-12-07       Impact factor: 4.849

3.  Cases: Reversible cerebellar syndrome caused by metronidazole.

Authors:  Justyna R Sarna; A Keith W Brownell; Sarah Furtado
Journal:  CMAJ       Date:  2009-09-14       Impact factor: 8.262

4.  Metronidazole-induced cerebellar toxicity.

Authors:  Jonathan A Chatzkel; Arastoo Vossough
Journal:  Pediatr Radiol       Date:  2009-11-14

5.  Reversible iatrogenic subacute cerebellar syndrome, myoclonus and MRI findings following metronidazole administration.

Authors:  Henda Foreid; Miguel Coelho; Joaquim Ferreira; José M Ferro
Journal:  BMJ Case Rep       Date:  2009-08-28

6.  Metronidazole-induced central and peripheral nervous system toxicity.

Authors:  G Cação; S Fontes; M Salgado; T Rodrigues; Joana Damásio
Journal:  Neurol Sci       Date:  2015-05-20       Impact factor: 3.307

7.  56-Year-Old Male With Acute-Onset Ataxia After Metronidazole Use and a Typical MRI Appearance.

Authors:  Dhananjay Duberkar; Rahul Baviskar
Journal:  Mov Disord Clin Pract       Date:  2015-07-25

8.  Metronidazole-induced encephalopathy: not always a reversible situation.

Authors:  Kyle Hobbs; Sara Stern-Nezer; Marion S Buckwalter; Nancy Fischbein; Anna Finley Caulfield
Journal:  Neurocrit Care       Date:  2015-06       Impact factor: 3.210

9.  Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis.

Authors:  Matthew W Carroll; Doosoo Jeon; James M Mountz; Jong Doo Lee; Yeon Joo Jeong; Nadeem Zia; Myungsun Lee; Jongseok Lee; Laura E Via; Soyoung Lee; Seok-Yong Eum; Sung-Joong Lee; Lisa C Goldfeder; Ying Cai; Boyoung Jin; Youngran Kim; Taegwon Oh; Ray Y Chen; Lori E Dodd; Wenjuan Gu; Veronique Dartois; Seung-Kyu Park; Cheon Tae Kim; Clifton E Barry; Sang-Nae Cho
Journal:  Antimicrob Agents Chemother       Date:  2013-06-03       Impact factor: 5.191

10.  Metronidazole-associated Neurologic Events: A Nested Case-control Study.

Authors:  Nick Daneman; Yi Cheng; Tara Gomes; Jun Guan; Muhammad M Mamdani; Farah E Saxena; David N Juurlink
Journal:  Clin Infect Dis       Date:  2021-06-15       Impact factor: 9.079

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