| Literature DB >> 18511090 |
He-Xiang Wang1, Chun-Mei Liu, Quan Liu, Kun Gao.
Abstract
Eight sesquiterpenes, including four guaiane-types containing an interesting epoxy unit (1-4), a rare tricyclic carbon skeleton-type (5) and three eudesmane-types (6-8), along with five known compounds, were isolated from rhizomes of Atractylodes lancea. The structures and relative configurations of 1-8 were determined by analysis of spectroscopic data, and the absolute configuration of 8 was assigned by application of the CD technique. Compounds 1, 2 and 4 were evaluated for their cytotoxic effects against P388 and A549 cells, but all were inactive. Possible biosynthetic pathways for sesquiterpenes (1-8) were discussed.Entities:
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Year: 2008 PMID： 18511090 DOI： 10.1016/j.phytochem.2008.04.008
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072