Literature DB >> 1851108

Evidence for the involvement of type II domains in collagen binding by 72 kDa type IV procollagenase.

L Bányai1, L Patthy.   

Abstract

The fibronectin-related region of the 72 kDa type IV procollagenase has been expressed in E. coli as a beta-galactosidase fusion product. The fragment containing the three type II units of the protein was found to have affinity for denatured collagen, suggesting that these domains may be responsible for the collagen-affinity of type IV collagenase. We have also shown that segment Ala-Ala-His-Glu of type IV collagenase (residues 372-375), which is similar to a fibronectin-segment previously implicated in collagen-binding, is not essential for binding activity.

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Year:  1991        PMID： 1851108     DOI： 10.1016/0014-5793(91)80436-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  15 in total

1.  The hairpin structure of the (6)F1(1)F2(2)F2 fragment from human fibronectin enhances gelatin binding.

Authors:  A R Pickford; S P Smith; D Staunton; J Boyd; I D Campbell
Journal:  EMBO J       Date:  2001-04-02       Impact factor: 11.598

2.  The NTR module: domains of netrins, secreted frizzled related proteins, and type I procollagen C-proteinase enhancer protein are homologous with tissue inhibitors of metalloproteases.

Authors:  L Bányai; L Patthy
Journal:  Protein Sci       Date:  1999-08       Impact factor: 6.725

3.  Origin of fibronectin type II (FN2) modules: structural analyses of distantly-related members of the kringle family idey the kringle domain of neurotrypsin as a potential link between FN2 domains and kringles.

Authors:  O A Ozhogina; M Trexler; L Bányai; M Llinás; L Patthy
Journal:  Protein Sci       Date:  2001-10       Impact factor: 6.725

4.  Binding of human plasminogen to basement-membrane (type IV) collagen.

Authors:  M S Stack; T L Moser; S V Pizzo
Journal:  Biochem J       Date:  1992-05-15       Impact factor: 3.857

5.  Functional basis for the overlap in ligand interactions and substrate specificities of matrix metalloproteinases-9 and -2.

Authors:  Xiaoping Xu; Zhihua Chen; Yao Wang; Yoshishige Yamada; Bjorn Steffensen
Journal:  Biochem J       Date:  2005-11-15       Impact factor: 3.857

6.  The gelatin-binding site of human 72 kDa type IV collagenase (gelatinase A).

Authors:  L Bányai; H Tordai; L Patthy
Journal:  Biochem J       Date:  1994-03-01       Impact factor: 3.857

7.  The relative orientation of the fibronectin 6F1(1)F2 module pair: a 15N NMR relaxation study.

Authors:  Y Hashimoto; S P Smith; A R Pickford; A A Bocquier; I D Campbell; J M Werner
Journal:  J Biomol NMR       Date:  2000-07       Impact factor: 2.835

8.  Nuclear magnetic resonance mapping and functional confirmation of the collagen binding sites of matrix metalloproteinase-2.

Authors:  Xiaoping Xu; Margarita Mikhailova; Udayar Ilangovan; Zhihua Chen; Agnes Yu; Sanjay Pal; Andrew P Hinck; Bjorn Steffensen
Journal:  Biochemistry       Date:  2009-06-30       Impact factor: 3.162

Review 9.  Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites.

Authors:  Christopher M Overall
Journal:  Mol Biotechnol       Date:  2002-09       Impact factor: 2.695

10.  Inhibition of MMP-2 gelatinolysis by targeting exodomain-substrate interactions.

Authors:  Xiaoping Xu; Zhihua Chen; Yao Wang; Lynda Bonewald; Bjorn Steffensen
Journal:  Biochem J       Date:  2007-08-15       Impact factor: 3.857
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