Literature DB >> 18506991

[Osteonecrosis of the jaws: a secondary effect of bisphosphonates].

J Schortinghuis1, L Meijndert, J G A M De Visscher, M J H Witjes.   

Abstract

When treated with intravenous bisphosphonates to prevent bone resorption, 4-10% of the patients may develop osteonecrosis of the jaws a side effect. The osteonecrosis is usually preceded by an invasive dental procedure such as the removal of a tooth. Treatment of the osteonecrosis should be conservative using aseptic mouth rinses, oral antibiotics and small debridement. It seems advisable to have a dental check-up before starting using intravenous bisphosphonates, since a potential dental infections can be treated before the bone healing capacity is reduced by the bisphosphonates.

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Year:  2007        PMID: 18506991

Source DB:  PubMed          Journal:  Rev Belge Med Dent (1984)        ISSN: 0775-0293


  1 in total

1.  Bisphosphonates are not associated with vertebral osteonecrosis.

Authors:  David F Kallmes; Arash Ehteshami Rad; Leigh A Gray; Robert J McDonald; Bart L Clarke
Journal:  J Bone Miner Metab       Date:  2009-03-27       Impact factor: 2.626

  1 in total

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