OBJECTIVE: The objective of this study was to evaluate the serum levels of tumor markers in patients with ovarian mature cystic teratomas. METHOD: Retrospective study of 215 patients operated at Zekai Tahir Burak Women Health Education and Research Hospital between January 2001 and October 2006 was performed. RESULTS: The median age was 36 years (range 13-80). The mean tumor diameter was 7.7 +/- 4.6 cm (range 2-25). The mean serum CA 125 level was 26.2 +/- 29.9 U/mL (range 1.4-225, normal value <35), and the mean serum CA 19-9 level was 83.5 +/- 179.2 IU/mL (range 0.6-1,000; normal value <37). The elevated rate of CA 19-9, CA 125 was 39.6% (74/187) and 23.3% (50/215), respectively. The mean age of patients and the rate of bilaterality of tumors were similar in both patients with elevated CA19-9 and with normal CA 19-9 level (P > 0.05). The mean tumor size of patients with elevated CA 19-9 was greater than those with normal CA19-9 level (P = 0.01). CONCLUSION: Serum CA 19-9 has the highest positivity rate among other tumor markers in ovarian mature cystic teratomas. Elevated serum CA 19-9 levels are correlated with larger tumor size. But the diagnostic value of elevated CA 19-9 in patients with MCT would be poor if the test was used alone.
OBJECTIVE: The objective of this study was to evaluate the serum levels of tumor markers in patients with ovarian mature cystic teratomas. METHOD: Retrospective study of 215 patients operated at Zekai Tahir Burak Women Health Education and Research Hospital between January 2001 and October 2006 was performed. RESULTS: The median age was 36 years (range 13-80). The mean tumor diameter was 7.7 +/- 4.6 cm (range 2-25). The mean serum CA 125 level was 26.2 +/- 29.9 U/mL (range 1.4-225, normal value <35), and the mean serum CA 19-9 level was 83.5 +/- 179.2 IU/mL (range 0.6-1,000; normal value <37). The elevated rate of CA 19-9, CA 125 was 39.6% (74/187) and 23.3% (50/215), respectively. The mean age of patients and the rate of bilaterality of tumors were similar in both patients with elevated CA19-9 and with normal CA 19-9 level (P > 0.05). The mean tumor size of patients with elevated CA 19-9 was greater than those with normal CA19-9 level (P = 0.01). CONCLUSION: Serum CA 19-9 has the highest positivity rate among other tumor markers in ovarian mature cystic teratomas. Elevated serum CA 19-9 levels are correlated with larger tumor size. But the diagnostic value of elevated CA 19-9 in patients with MCT would be poor if the test was used alone.
Authors: M J Titulaer; R Soffietti; J Dalmau; N E Gilhus; B Giometto; F Graus; W Grisold; J Honnorat; P A E Sillevis Smitt; R Tanasescu; C A Vedeler; R Voltz; J J G M Verschuuren Journal: Eur J Neurol Date: 2010-09-29 Impact factor: 6.089
Authors: Milan M Terzic; Jelena Dotlic; Ivana Likic; Nebojsa Ladjevic; Natasa Brndusic; Nebojsa Arsenovic; Sanja Maricic; Tihomir Mihailovic; Sasa Andrijasevic Journal: Chin J Cancer Res Date: 2013-02 Impact factor: 5.087
Authors: Dong Soo Suh; Soo Hyun Moon; Seung Cheol Kim; Jong Kil Joo; Won Young Park; Ki Hyung Kim Journal: World J Surg Oncol Date: 2014-11-22 Impact factor: 2.754