Literature DB >> 18505528

The effects of topical l(+) lactic Acid and ascorbic Acid on skin whitening.

W P Smith1.   

Abstract

Subjects with medium to dark skin and many exhibiting facial age spots or discolorations participated in this twelve week study to evaluate the skin whitening ability of lactic and ascorbic acid. Using clinical and biophysical test methods we observed prolonged treatment with 8.8% L(+) lactic acid resulted in no significant effects on skin pigmentation. However treatment with L(+) lactic acid supplemented with ascorbic acid (1%) did produce a whitening effect which becomes apparent after three months. These effects were demonstrated clinically by the test panelists, and trained clinicians, and with objective instrumental methods. We observed a general skin lightening and did see a modest preferential lightening of age spots with the combination of acids.

Entities:  

Year:  1999        PMID: 18505528     DOI: 10.1046/j.1467-2494.1999.196561.x

Source DB:  PubMed          Journal:  Int J Cosmet Sci        ISSN: 0142-5463            Impact factor:   2.970


  3 in total

1.  Magnesium ascorbyl phosphate vesicular carriers for topical delivery; preparation, in-vitro and ex-vivo evaluation, factorial optimization and clinical assessment in melasma patients.

Authors:  Soha M Kandil; Iman I Soliman; Heba M Diab; Nermeen I Bedair; Marwa H Mahrous; Ebtsam M Abdou
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.819

2.  Evaluation of depigmenting activity by 8-hydroxydaidzein in mouse B16 melanoma cells and human volunteers.

Authors:  Sorgan Shou-Ku Tai; Ching-Gong Lin; Mon-Han Wu; Te-Sheng Chang
Journal:  Int J Mol Sci       Date:  2009-11-20       Impact factor: 6.208

Review 3.  Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds.

Authors:  Marjan Nassiri Asl; Hossein Hosseinzadeh
Journal:  Phytother Res       Date:  2008-06       Impact factor: 5.878

  3 in total

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