| Literature DB >> 1850450 |
G E Dale1, P N Leigh, P Luthert, B H Anderton, G W Roberts.
Abstract
Ubiquitin, a protein thought to be involved in the ATP-dependent non-lysosomal degradation of abnormal proteins, has already been identified as a component of neurofibrillary tangles in Alzheimer's disease. We have examined ubiquitin immunoreactivity in a unique collection of brains from 16 ex-boxers including 11 with dementia pugilistica. Neurofibrillary tangles of dementia pugilistica were labelled with an affinity purified antiserum to ubiquitin, and BF10, a monoclonal antibody to a neurofilament epitope.Entities:
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Year: 1991 PMID: 1850450 PMCID: PMC1014344 DOI: 10.1136/jnnp.54.2.116
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154