Literature DB >> 1850445

Influence of pore dimensions on bone ingrowth into porous hydroxylapatite blocks used as bone graft substitutes. A histometric study.

H Schliephake1, F W Neukam, D Klosa.   

Abstract

The aim of the present study was to determine the influence of pore dimensions of porous hydroxylapatite (HA) blocks on bone ingrowth when used as interposed grafts in alveolar ridge bone defects. HA blocks with pore diameters of 150 microns and 260 microns were used. Ten animals received one implant each with small pore sizes, whilst in 10 other animals blocks with larger pore sizes were used. The blocks were examined histometrically and spatially reconstructed for determination of 3-dimensional distribution of bone ingrowth. In the group of implants with 150 microns pore diameter a high rate of implant loss occurred. The blocks with 260 microns pore diameter had 3 times more bone ingrowth compared with the 150 microns group with uniform distribution.

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Year:  1991        PMID: 1850445     DOI: 10.1016/s0901-5027(05)80698-8

Source DB:  PubMed          Journal:  Int J Oral Maxillofac Surg        ISSN: 0901-5027            Impact factor:   2.789


  15 in total

1.  Osseointegration and osseoconductivity of hydroxyapatite of different microporosities.

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2.  Development of a new synthetic bone graft.

Authors:  D C Tancred; A J Carr; B A McCormack
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3.  Development of graded hydroxyapatite/CaCO(3) composite structures for bone ingrowth.

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Journal:  J Mater Sci Mater Med       Date:  2007-05-05       Impact factor: 3.896

4.  Integration of a novel injectable nano calcium sulfate/alginate scaffold and BMP2 gene-modified mesenchymal stem cells for bone regeneration.

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Journal:  Tissue Eng Part A       Date:  2012-11-16       Impact factor: 3.845

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6.  Electrospun PLGA and β-TCP (Rebossis-85) in a Lapine Posterolateral Fusion Model.

Authors:  J Christopher Nepola; Emily B Petersen; Nicole DeVries-Watson; Nicole Grosland; Douglas C Fredericks
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Review 7.  Calcium Orthophosphate-Based Bioceramics.

Authors:  Sergey V Dorozhkin
Journal:  Materials (Basel)       Date:  2013-09-06       Impact factor: 3.623

8.  Effects of Addition of Mannitol Crystals on the Porosity and Dissolution Rates of a Calcium Phosphate Cement.

Authors:  Debra Vazquez; Shozo Takagi; Stan Frukhtbeyn; Laurence C Chow
Journal:  J Res Natl Inst Stand Technol       Date:  2010-08-01

9.  Formation of macropores in calcium phosphate cement implants.

Authors:  S Takagi; L C Chow
Journal:  J Mater Sci Mater Med       Date:  2001-02       Impact factor: 3.896

10.  Scaffolds with a standardized macro-architecture fabricated from several calcium phosphate ceramics using an indirect rapid prototyping technique.

Authors:  C E Wilson; C A van Blitterswijk; A J Verbout; W J A Dhert; J D de Bruijn
Journal:  J Mater Sci Mater Med       Date:  2010-11-11       Impact factor: 3.896

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