| Literature DB >> 18504074 |
Aboudoulatif Diallo1, Messanvi Gbeassor, Ahoefa Vovor, Kwashie Eklu-Gadegbeku, Kodjo Aklikokou, Amegnona Agbonon, Ange A Abena, Comla de Souza, Koffi Akpagana.
Abstract
Traditional oral report indicates that Tectona grandis is used in the treatment of anaemia in Togo. For this purpose, the extract of T. grandis leaves is evaluated on anaemia model of rat induced by intraperitoneal injection of phenylhydrazine at 40 mg/kg for 2 days. Oral administration of T. grandis extract at 1 g/kg/day and 2 g/kg/day, to the rats previously treated with phenylhydrazine, increased the concentration of haemoglobin, red blood cells number, haematocrit and reticulocytes rate. Moreover, the extract of T. grandis enhanced the osmotic resistance of the red blood cells that confirm the important presence of young red blood cells. These results support partially the traditional use of T. grandis in the treatment of anaemia.Entities:
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Year: 2008 PMID： 18504074 DOI： 10.1016/j.fitote.2008.02.005
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882