Literature DB >> 18502905

The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology.

Megan L Krajewski, Lewis L Hsu, Mark T Gladwin.   

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Year:  2008        PMID： 18502905      PMCID： PMC2494755          DOI： 10.1152/ajpheart.00499.2008

Source DB:  PubMed          Journal:  Am J Physiol Heart Circ Physiol        ISSN： 0363-6135            Impact factor:   4.733


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  33 in total

1.  Modulation of Gardos channel activity by cytokines in sickle erythrocytes.

Authors:  Alicia Rivera; Petr Jarolim; Carlo Brugnara
Journal:  Blood       Date:  2002-01-01       Impact factor: 22.113

2.  Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease.

Authors:  M Aslan; T M Ryan; B Adler; T M Townes; D A Parks; J A Thompson; A Tousson; M T Gladwin; R P Patel; M M Tarpey; I Batinic-Haberle; C R White; B A Freeman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

3.  Direct real-time evaluation of nitration with green fluorescent protein in solution and within human cells reveals the impact of nitrogen dioxide vs. peroxynitrite mechanisms.

Authors:  Michael Graham Espey; Sandhya Xavier; Douglas D Thomas; Katrina M Miranda; David A Wink
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-19       Impact factor: 11.205

4.  Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease.

Authors:  Christopher D Reiter; Xunde Wang; Jose E Tanus-Santos; Neil Hogg; Richard O Cannon; Alan N Schechter; Mark T Gladwin
Journal:  Nat Med       Date:  2002-11-11       Impact factor: 53.440

Review 5.  Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress.

Authors:  H Cai; D G Harrison
Journal:  Circ Res       Date:  2000-11-10       Impact factor: 17.367

6.  A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.

Authors:  Marie-Luise Brennan; Weijia Wu; Xiaoming Fu; Zhongzhu Shen; Wei Song; Heather Frost; Caryn Vadseth; Laura Narine; Elizabeth Lenkiewicz; Michael T Borchers; Aldons J Lusis; James J Lee; Nancy A Lee; Husam M Abu-Soud; Harry Ischiropoulos; Stanley L Hazen
Journal:  J Biol Chem       Date:  2002-02-27       Impact factor: 5.157

7.  Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.

Authors:  José R Romero; Sandra M Suzuka; Ronald L Nagel; Mary E Fabry
Journal:  Blood       Date:  2002-02-15       Impact factor: 22.113

8.  Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.

Authors:  Dhananjay K Kaul; Xiaoqin Zhang; Trisha Dasgupta; Mary E Fabry
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-05-02       Impact factor: 4.733

9.  Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction.

Authors:  Douglas D Thomas; Michael Graham Espey; Michael P Vitek; Katrina M Miranda; David A Wink
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-11       Impact factor: 11.205

10.  Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation.

Authors:  Renliang Zhang; Marie-Luise Brennan; Zhongzhou Shen; Jennifer C MacPherson; Dave Schmitt; Cheryl E Molenda; Stanley L Hazen
Journal:  J Biol Chem       Date:  2002-09-30       Impact factor: 5.157
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  8 in total

1.  Antisickling property of fetal hemoglobin enhances nitric oxide bioavailability and ameliorates organ oxidative stress in transgenic-knockout sickle mice.

Authors:  Trisha Dasgupta; Mary E Fabry; Dhananjay K Kaul
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2009-12-09       Impact factor: 3.619

Review 2.  Heme degradation and vascular injury.

Authors:  John D Belcher; Joan D Beckman; Gyorgy Balla; Jozsef Balla; Gregory Vercellotti
Journal:  Antioxid Redox Signal       Date:  2010-02       Impact factor: 8.401

3.  Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease.

Authors:  Alex George; Suvarnamala Pushkaran; Diamantis G Konstantinidis; Sebastian Koochaki; Punam Malik; Narla Mohandas; Yi Zheng; Clinton H Joiner; Theodosia A Kalfa
Journal:  Blood       Date:  2013-01-24       Impact factor: 22.113

4.  A systems biology consideration of the vasculopathy of sickle cell anemia: the need for multi-modality chemo-prophylaxsis.

Authors:  Robert P Hebbel; Greg Vercellotti; Karl A Nath
Journal:  Cardiovasc Hematol Disord Drug Targets       Date:  2009-12

5.  Nitric oxide pathology and therapeutics in sickle cell disease.

Authors:  Daniel B Kim-Shapiro; Mark T Gladwin
Journal:  Clin Hemorheol Microcirc       Date:  2018       Impact factor: 2.375

6.  Inflammation in sickle cell disease.

Authors:  Nicola Conran; John D Belcher
Journal:  Clin Hemorheol Microcirc       Date:  2018       Impact factor: 2.375

7.  Experimental priapism is associated with increased oxidative stress and activation of protein degradation pathways in corporal tissue.

Authors:  N D Kanika; A Melman; K P Davies
Journal:  Int J Impot Res       Date:  2010-11-18       Impact factor: 2.896

Review 8.  Heme Degradation in Pathophysiology of and Countermeasures to Inflammation-Associated Disease.

Authors:  Donald David Haines; Arpad Tosaki
Journal:  Int J Mol Sci       Date:  2020-12-18       Impact factor: 5.923
  8 in total

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