Literature DB >> 18501656

The alpha4beta1 integrin in sickle cell disease.

J E Brittain1, L V Parise.   

Abstract

The alpha4beta1 integrin is an adhesion receptor expressed on reticulocytes in sickle cell disease (SCD) and mediates the adhesion of these cells to sub-endothelial matrix proteins and the endothelium. In this review, we describe the mechanism of activation of the alpha4beta1 integrin on sickle reticulocytes and discuss novel roles for this integrin in SCD as a result of this activation. We also illustrate novel therapies in SCD that may target the integrin and alleviate vaso-occlusion.

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Year:  2008        PMID： 18501656     DOI： 10.1016/j.tracli.2008.03.013

Source DB:  PubMed          Journal:  Transfus Clin Biol        ISSN： 1246-7820            Impact factor:   1.406


  10 in total

1.  Proteolipidic composition of exosomes changes during reticulocyte maturation.

Authors:  Kévin Carayon; Karima Chaoui; Elsa Ronzier; Ikrame Lazar; Justine Bertrand-Michel; Véronique Roques; Stéphanie Balor; François Terce; André Lopez; Laurence Salomé; Etienne Joly
Journal:  J Biol Chem       Date:  2011-08-02       Impact factor: 5.157

Review 2.  Proteomic and biomarker studies and neurological complications of pediatric sickle cell disease.

Authors:  Eboni I Lance; James F Casella; Allen D Everett; Emily Barron-Casella
Journal:  Proteomics Clin Appl       Date:  2014-11-06       Impact factor: 3.494

3.  Clinical and laboratory parameters, risk factors predisposing to the development of priapism in sickle cell patients.

Authors:  Salam Alkindi; Said S Almufargi; Anil Pathare
Journal:  Exp Biol Med (Maywood)       Date:  2019-12-06

Review 4.  Priapism in sickle-cell disease: a hematologist's perspective.

Authors:  Gregory J Kato
Journal:  J Sex Med       Date:  2011-05-06       Impact factor: 3.802

5.  Activation state of alpha4beta1 integrin on sickle red blood cells is linked to the duffy antigen receptor for chemokines (DARC) expression.

Authors:  Marie-Claude Durpès; Marie-Dominique Hardy-Dessources; Wassim El Nemer; Julien Picot; Nathalie Lemonne; Jacques Elion; Monique Decastel
Journal:  J Biol Chem       Date:  2010-11-18       Impact factor: 5.157

Review 6.  Pleiotropic effects of intravascular haemolysis on vascular homeostasis.

Authors:  Gregory J Kato; James G Taylor
Journal:  Br J Haematol       Date:  2009-12-01       Impact factor: 6.998

7.  Vasculopathy in sickle cell disease: Biology, pathophysiology, genetics, translational medicine, and new research directions.

Authors:  Gregory J Kato; Robert P Hebbel; Martin H Steinberg; Mark T Gladwin
Journal:  Am J Hematol       Date:  2009-09       Impact factor: 10.047

8.  Process and procedural adjustments to improve CD34+ collection efficiency of hematopoietic progenitor cell collections in sickle cell disease.

Authors:  Scott T Avecilla; Farid Boulad; Karina Yazdanbakhsh; Michel Sadelain; Patricia A Shi
Journal:  Transfusion       Date:  2021-06-23       Impact factor: 3.337

Review 9.  Management of sickle cell disease: a review for physician education in Nigeria (sub-saharan Africa).

Authors:  Ademola Samson Adewoyin
Journal:  Anemia       Date:  2015-01-18

10.  Proteomics study of human cord blood reticulocyte-derived exosomes.

Authors:  Míriam Díaz-Varela; Armando de Menezes-Neto; Daniel Perez-Zsolt; Ana Gámez-Valero; Joan Seguí-Barber; Nuria Izquierdo-Useros; Javier Martinez-Picado; Carmen Fernández-Becerra; Hernando A Del Portillo
Journal:  Sci Rep       Date:  2018-09-19       Impact factor: 4.379
  10 in total

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