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Literature DB >> 18499027

Enteric autoantibodies and gut motility disorders.

Abstract

Increasing evidence suggests that a subset of gastrointestinal motility disorders is associated with the presence of circulating antibodies. These antibodies are directed against various molecular targets, the best known being anti-neuronal nuclear antibody (ANNA-1 or anti-Hu) associated with paraneoplastic motility disorders. There is also evidence that the presence of distinct autoantibody profiles is associated with non-paraneoplastic motility disorders. This review focuses on the types of antibodies associated with gastrointestinal motility disorders and the significance of these antibodies. Algorithms are suggested for the work-up and treatment of patients with circulating antibodies associated with gastrointestinal motility disorders.

Entities: Disease Species

Mesh：

Substances：
Autoantibodies

Year: 2008 PMID： 18499027 PMCID： PMC2448392 DOI： 10.1016/j.gtc.2008.02.005

Source DB: PubMed Journal: Gastroenterol Clin North Am ISSN： 0889-8553 Impact factor: 3.806

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12 in total

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Review 3. Immunity, Ion Channels and Epilepsy.

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