Literature DB >> 18498817

In-patient international normalized ratio self-testing instruction after mechanical heart valve implantation.

Jess L Thompson1, Thoralf M Sundt, Maurice E Sarano, Paula J Santrach, Hartzell V Schaff.   

Abstract

BACKGROUND: Patient self-testing of the international normalized ratio (INR) has been shown to improve management of anticoagulation with warfarin and reduce risks of thromboembolism and bleeding. Self-testing instruction usually begins several weeks after hospital discharge. We evaluated the feasibility of in-hospital INR self-testing instruction in patients recovering from valve replacement.
METHODS: We instituted an education program on a self-testing device before hospital discharge in 50 adult patients (median age, 54 years; 66% men) undergoing cardiac valve replacement with mechanical prostheses. Patients were monitored for 1 month to assess their ability to self-test and the accuracy of the INR measurements.
RESULTS: Self-testing instruction began on postoperative day 4 (range, 1 to 8 days). Each patient had an average of 3.5 teaching sessions; each session lasted approximately 20 minutes. One month after discharge, all patients (98%) but 1 were able to self-test. No patient required interval instruction. One bleeding episode occurred in a patient whose INR exceeded the therapeutic range. Once warfarin doses were stabilized, 5 patients had subtherapeutic INR values on self-testing. The mean INR test result obtained from the coagulometer correlated well with values obtained by laboratory determination (r = 0.79).
CONCLUSIONS: This evaluation of an in-hospital education program demonstrates that patients are able to learn INR self-testing and that most will continue to use the method without the need for interval instruction. Improved anticoagulation management by early introduction of INR self-testing should reduce thromboembolic and hemorrhagic complications after valve replacement.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18498817     DOI: 10.1016/j.athoracsur.2008.01.051

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  2 in total

1.  Security and cost comparison of INR self-testing and conventional hospital INR testing in patients with mechanical heart valve replacement.

Authors:  Qiu-lin Chen; Li Dong; Yi-jun Dong; Shu-lin Zhao; Bo Fu; Yu-qing Wang; Hong Jiang
Journal:  J Cardiothorac Surg       Date:  2015-01-16       Impact factor: 1.637

2.  Self-management of patients with heart valve replacement and its clinical outcomes: a systematic review.

Authors:  Shirdel Zandi; Behzad Imani; Gholamreza Safarpor; Salman Khazaei
Journal:  Kardiochir Torakochirurgia Pol       Date:  2021-05-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.