Literature DB >> 18498491

Causes of hair loss and the developments in hair rejuvenation.

D H Rushton1, M J Norris, R Dover, Nina Busuttil.   

Abstract

Hair is considered to be a major component of an individual's general appearance. The psychological impact of hair loss results in a measurably detrimental change in self-esteem and is associated with images of reduced worth. It is not surprising that both men and women find hair loss a stressful experience. Genetic hair loss is the major problem affecting men and by the age of 50, up to 50% will be affected. Initial attempts to regenerate the lost hair have centred on applying a topical solution of between 2% to 5% minoxidil; however, the results proved disappointing. Recently, finasteride, a type II 5alpha reductase inhibitor has been found to regrow a noticeable amount of hair in about 40% of balding men. Further developments in treatments have lead to the use of a dual type I and type II inhibitor where 90% of those treated regrow a noticeable amount of hair. In women the major cause of hair loss before the age of 50 is nutritional, with 30% affected. Increased and persistent hair shedding (chronic telogen effluvium) and reduced hair volume are the principle changes occurring. The main cause appears to be depleted iron stores, compromised by a suboptimal intake of the essential amino acid l-lysine. Correction of these imbalances stops the excessive hair loss and returns the hair back to its former glory. However, it can take many months to redress the situation.

Entities:  

Year:  2002        PMID: 18498491     DOI: 10.1046/j.0412-5463.2001.00110.x

Source DB:  PubMed          Journal:  Int J Cosmet Sci        ISSN: 0142-5463            Impact factor:   2.970


  15 in total

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4.  Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders.

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Journal:  Int J Mol Sci       Date:  2017-02-03       Impact factor: 5.923

5.  Diet and hair loss: effects of nutrient deficiency and supplement use.

Authors:  Emily L Guo; Rajani Katta
Journal:  Dermatol Pract Concept       Date:  2017-01-31

6.  Effects of Decursin and Angelica gigas Nakai Root Extract on Hair Growth in Mouse Dorsal Skin via Regulating Inflammatory Cytokines.

Authors:  Tae-Kyeong Lee; Bora Kim; Dae Won Kim; Ji Hyeon Ahn; Hyejin Sim; Jae-Chul Lee; Go Eun Yang; Young Her; Joon Ha Park; Hyun Sook Kim; Tae Heung Sim; Hyun Sam Lee; Moo-Ho Won
Journal:  Molecules       Date:  2020-08-13       Impact factor: 4.411

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Authors:  Meriem Bejaoui; Myra O Villareal; Hiroko Isoda
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8.  Iron plays a certain role in patterned hair loss.

Authors:  Song Youn Park; Se Young Na; Jun Hwan Kim; Soyun Cho; Jong Hee Lee
Journal:  J Korean Med Sci       Date:  2013-06-03       Impact factor: 2.153

Review 9.  Nutrition of women with hair loss problem during the period of menopause.

Authors:  Zuzanna Sabina Goluch-Koniuszy
Journal:  Prz Menopauzalny       Date:  2016-03-29

10.  Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth.

Authors:  Dong Ho Bak; Mi Ji Choi; Soon Re Kim; Byung Chul Lee; Jae Min Kim; Eun Su Jeon; Wonil Oh; Ee Seok Lim; Byung Cheol Park; Moo Joong Kim; Jungtae Na; Beom Joon Kim
Journal:  Korean J Physiol Pharmacol       Date:  2018-08-27       Impact factor: 2.016

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