Literature DB >> 1849843

DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems.

B Halliwell1, O I Aruoma.   

Abstract

When cells are exposed to oxidative stress, DNA damage frequently occurs. The molecular mechanisms causing this damage may include activation of nucleases and direct reaction of hydroxyl radicals with the DNA. Several oxygen-derived species can attack DNA, producing distinctive patterns of chemical modification. Observation of these patterns and measurement of some of the products formed has been used to determine the role of different oxygen-derived species in DNA cleavage reactions, to assess the extent of oxidative damage to DNA in vivo and to investigate the mechanism of DNA damage by ionizing radiation and chemical carcinogens.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 1849843     DOI: 10.1016/0014-5793(91)80347-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  219 in total

1.  Clusters of S1 nuclease-hypersensitive sites induced in vivo by DNA damage.

Authors:  J Legault; A Tremblay; D Ramotar; M E Mirault
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

Review 2.  A free-radical hypothesis for the instability and evolution of genotype and phenotype in vitro.

Authors:  R E Parchment; K Natarajan
Journal:  Cytotechnology       Date:  1992       Impact factor: 2.058

Review 3.  Does the mitochondrial DNA play a role in the pathogenesis of diabetes?

Authors:  K D Gerbitz
Journal:  Diabetologia       Date:  1992-12       Impact factor: 10.122

4.  S. choloroleuca, S. mirzayanii and S. santolinifolia protect PC12 cells from H(2)O (2)-induced apoptosis by blocking the intrinsic pathway.

Authors:  Shabnam Zeighamy Alamdary; Fariba Khodagholi; Fatemeh Shaerzadeh; Niloufar Ansari; Ali Sonboli; Solaleh Khoramian Tusi
Journal:  Cytotechnology       Date:  2011-12-31       Impact factor: 2.058

5.  Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry.

Authors:  F Wang; P Jiao; M Qi; M Frezza; Q P Dou; B Yan
Journal:  Curr Med Chem       Date:  2010       Impact factor: 4.530

6.  cagA and vacA status and influence of Helicobacter pylori infection on serum oxidative DNA damage in Iranian patients with peptic ulcer disease.

Authors:  Z Khodaii; S M H Ghaderian; R Akbarzadeh Najar; H Nejati; A S Tabatabaei Panah
Journal:  Ir J Med Sci       Date:  2010-08-20       Impact factor: 1.568

7.  Differential role of hydrogen peroxide in UV-induced signal transduction.

Authors:  Min Ding; Jingxia Li; Stephen S Leonard; Xianglin Shi; Max Costa; Vincent Castranova; Val Vallyathan; Chuanshu Huang
Journal:  Mol Cell Biochem       Date:  2002 May-Jun       Impact factor: 3.396

8.  Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.

Authors:  Margarita Tenopoulou; Paschalis-Thomas Doulias; Alexandra Barbouti; Ulf Brunk; Dimitrios Galaris
Journal:  Biochem J       Date:  2005-05-01       Impact factor: 3.857

9.  Protective effect of carnosine and N-acetylcysteine against sodium nitrite-induced oxidative stress and DNA damage in rat intestine.

Authors:  Fariheen Aisha Ansari; Aijaz Ahmed Khan; Riaz Mahmood
Journal:  Environ Sci Pollut Res Int       Date:  2018-05-04       Impact factor: 4.223

10.  Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury.

Authors:  Arnold Groehler; Stefan Kren; Qinglu Li; Maggie Robledo-Villafane; Joshua Schmidt; Mary Garry; Natalia Tretyakova
Journal:  Free Radic Biol Med       Date:  2018-03-11       Impact factor: 7.376

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.