Literature DB >> 18498422

An evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation.

Chris G McMahon1, Stanley Althof, Marcel D Waldinger, Hartmut Porst, John Dean, Ira Sharlip, P G Adaikan, Edgardo Becher, Gregory A Broderick, Jacques Buvat, Khalid Dabees, Annamaria Giraldi, François Giuliano, Wayne J G Hellstrom, Luca Incrocci, Ellen Laan, Eric Meuleman, Michael A Perelman, Raymond Rosen, David Rowland, Robert Segraves.   

Abstract

OBJECTIVE: To develop a contemporary, evidence-based definition of premature ejaculation (PE).
METHODS: There are several definitions of PE; the most commonly quoted, the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders - 4th Edition - Text Revision, and other definitions of PE, are all authority-based rather than evidence-based, and have no support from controlled clinical and/or epidemiological studies. Thus in August 2007, the International Society for Sexual Medicine (ISSM) appointed several international experts in PE to an Ad Hoc Committee for the Definition of PE. The committee met in Amsterdam in October 2007 to evaluate the strengths and weaknesses of current definitions of PE, to critically assess the evidence in support of the constructs of ejaculatory latency, ejaculatory control, sexual satisfaction and personal/interpersonal distress, and to propose a new evidence-based definition of PE.
RESULTS: The Committee unanimously agreed that the constructs which are necessary to define PE are rapidity of ejaculation, perceived self-efficacy, and control and negative personal consequences from PE. The Committee proposed that lifelong PE be defined as a male sexual dysfunction characterized by ejaculation which always or nearly always occurs before or within about one minute of vaginal penetration, and the inability to delay ejaculation on all or nearly all vaginal penetrations, and negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy. This definition is limited to men with lifelong PE who engage in vaginal intercourse. The panel concluded that there are insufficient published objective data to propose an evidence-based definition of acquired PE.
CONCLUSION: The ISSM definition of lifelong PE represents the first evidence-based definition of PE. This definition will hopefully lead to the development of new tools and patient-reported outcome measures for diagnosing and assessing the efficacy of treatment interventions, and encourage ongoing research into the true prevalence of this disorder, and the efficacy of new pharmacological and psychological treatments.

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Year:  2008        PMID: 18498422     DOI: 10.1111/j.1464-410X.2008.07755.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  30 in total

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Authors:  Sheridan M Hoy; Lesley J Scott
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5.  Evolving therapeutic strategies for premature ejaculation: The search for on-demand treatment - topical versus systemic.

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Journal:  Can Urol Assoc J       Date:  2012-10       Impact factor: 1.862

Review 6.  New insights on premature ejaculation: a review of definition, classification, prevalence and treatment.

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Review 7.  Recent advances in the treatment of premature ejaculation.

Authors:  Kate D Linton; Kevan R Wylie
Journal:  Drug Des Devel Ther       Date:  2010-02-18       Impact factor: 4.162

8.  Frequency of etiological factors among patients with acquired premature ejaculation: prospective, observational, single-center study.

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Review 9.  Psychological intervention for premature ejaculation.

Authors:  Tamara Melnik; Sidney Glina; Oswaldo M Rodrigues
Journal:  Nat Rev Urol       Date:  2009-08-04       Impact factor: 14.432

10.  Phosphodiesterase Type 5 Inhibitors for Premature Ejaculation: A Systematic Review and Meta-analysis.

Authors:  Marrissa Martyn-St James; Katy Cooper; Shijie Ren; Eva Kaltenthaler; Kath Dickinson; Anna Cantrell; Kevan Wylie; Leila Frodsham; Catherine Hood
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