Literature DB >> 18498147

Changes of the hepatic proteome in hepatitis B-infected mouse model at early stages of fibrosis.

Daniela Spano1, Flora Cimmino, Mario Capasso, Fulvio D'Angelo, Nicola Zambrano, Luigi Terracciano, Achille Iolascon.   

Abstract

Liver fibrosis (LF) is the accumulation of extracellular matrix (ECM) proteins due to chronic liver injury. We used two-dimensional differential in-gel electrophoresis (2D-DIGE) to perform a comparative analysis of cytosolic and nuclear protein patterns of nontransgenic (NTg) and HBV transgenic (Tg) mice livers at early stages of fibrosis. We identified several candidate proteins, involved in a variety of pathways, which could be used as putative biomarkers for LF early detection.

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Year:  2008        PMID： 18498147     DOI： 10.1021/pr7006522

Source DB:  PubMed          Journal:  J Proteome Res        ISSN： 1535-3893            Impact factor:   4.466


  5 in total

1.  Dipyridamole prevents triple-negative breast-cancer progression.

Authors:  Daniela Spano; Jean-Claude Marshall; Natascia Marino; Daniela De Martino; Alessia Romano; Maria Nunzia Scoppettuolo; Anna Maria Bello; Valeria Di Dato; Luigi Navas; Gennaro De Vita; Chiara Medaglia; Patricia S Steeg; Massimo Zollo
Journal:  Clin Exp Metastasis       Date:  2012-07-04       Impact factor: 5.150

2.  Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease.

Authors:  Irina A Kirpich; Leila N Gobejishvili; Marjorie Bon Homme; Sabine Waigel; Matt Cave; Gavin Arteel; Shirish S Barve; Craig J McClain; Ion V Deaciuc
Journal:  J Nutr Biochem       Date:  2010-03-20       Impact factor: 6.048

Review 3.  Hepatitis B virus large surface protein: function and fame.

Authors:  Yuri Churin; Martin Roderfeld; Elke Roeb
Journal:  Hepatobiliary Surg Nutr       Date:  2015-02       Impact factor: 7.293

4.  Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model.

Authors:  Fangming Kan; Lei Ye; Tao Yan; Jiaqi Cao; Jianhua Zheng; Wuping Li
Journal:  BMC Genomics       Date:  2017-08-22       Impact factor: 3.969

5.  Pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background.

Authors:  Yuri Churin; Martin Roderfeld; Johannes Stiefel; Tilman Würger; Dirk Schröder; Tomomitsu Matono; Hans-Joachim Mollenkopf; Roberta Montalbano; Malvika Pompaiah; Kurt Reifenberg; Daniel Zahner; Matthias Ocker; Wolfram Gerlich; Dieter Glebe; Elke Roeb
Journal:  PLoS One       Date:  2014-03-04       Impact factor: 3.240
  5 in total

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