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Literature DB >> 18498027

Cardiac granulocytic sarcoma diagnosed by intracardiac echocardiography-guided biopsy.

Mirta Koželj¹, Darko Zorman², Blaž Mrevlje², Peter Černelč³, Samo Zver³.

Abstract

A 52-year-old man presented with clinical and echocardiographic signs of cardiac tamponade. A transthoracic echocardiogram revealed a large right atrial mass that obstructed the superior vena cava flow. Cardiac magnetic resonance imaging and computed tomography demonstrated extracardiac tumour invasion of the free atrial wall extending to the right pulmonary hilus. Intracardiac echocardiography-guided biopsy of the tumour revealed the tissue diagnosis-granulocytic sarcoma of the heart. The patient was effectively treated with radiotherapy, chemotherapy and allogeneic haematopoietic stem cell transplantation. He has remained free of the disease for 12 months after treatment.

Entities: Disease Species

Mesh：

Year: 2008 PMID： 18498027 DOI： 10.1007/s12185-008-0104-5

Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490

9 in total

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9 in total

6 in total

Cardiac granulocytic sarcoma diagnosed by intracardiac echocardiography-guided biopsy.

1. [Multifocal chloroma (granulocytic sarcoma), without marrow involvement. One case (author's transl)].

2. Granulocytic sarcoma of the heart: extramedullary relapse of acute myeloblastic leukemia after allogeneic stem cell transplantation successfully treated by chemotherapy alone.

3. [Mitral valve stenosis due to primary cardiac granulocytic sarcoma relapsing 8 years after complete remission: a case report].

4. Aleukemic granulocytic sarcoma with AML1/ETO fusion gene expression and clonal T cell populations.

5. Extra-medullary myeloid tumour (granulocytic sarcoma) is often misdiagnosed: a study of 26 cases.

Review 6. Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention.

7. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.

8. Nonleukemic granulocytic sarcoma of the heart: a report of a fatal case.

Review 9. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

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