Literature DB >> 18497733

Ethnic disparities in stroke and hypertension among women: the BASIC project.

Lynda D Lisabeth1, Melinda A Smith, Brisa N Sánchez, Devin L Brown.   

Abstract

BACKGROUND: Little data exist on stroke burden in Mexican-American (MA) women. The objective of this study was to characterize the burden of stroke in MA and non-Hispanic white (NHW) women and to compare this burden across ethnic groups.
METHODS: Cases of ischemic stroke and intracerebral hemorrhage among women (January 2000-December 2006) were identified as part of the Brain Attack Surveillance in Corpus Christi (BASIC) Project, a stroke surveillance study in a biethnic Texas community. Cumulative incidence of stroke among women was compared by ethnicity and age. Logistic regression was used to compare risk factors and age-adjusted use of antihypertensives between MA and NHW female stroke cases.
RESULTS: MA women had elevated stroke risk compared with NHW women at younger ages (ages 45-59: relative risk (RR) = 2.00 (95% confidence interval (CI): 1.54-2.58); ages 60-74: RR = 1.57 (95% CI: 1.31-1.87); ages > or =75: RR = 1.13 (95% CI: 0.98-1.29)). Stroke severity and stroke type did not differ between ethnic groups. MA female stroke cases were more likely to have hypertension (odds ratio (OR) = 1.41 (95% CI: 1.11-1.80)), diabetes (OR = 3.54 (95% CI: 2.82-4.45)), and the presence of both risk factors (OR = 3.31 (95% CI: 2.61-4.21)) compared with NHW female stroke cases and were more likely to report use of antihypertensives (OR = 1.51 (95% CI: 1.10-2.06)). There was a trend toward greater hypertension awareness among MA female stroke cases (OR = 1.37 (95% CI: 0.98-1.91)).
CONCLUSIONS: MA women have increased risk of stroke at younger ages compared with NHW women. Reasons for this ethnic disparity, including an increased prevalence of hypertension and diabetes, should be explored.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18497733     DOI: 10.1038/ajh.2008.161

Source DB:  PubMed          Journal:  Am J Hypertens        ISSN: 0895-7061            Impact factor:   2.689


  7 in total

Review 1.  Ancel Keys Lecture: Adventures (and misadventures) in understanding (and reducing) disparities in stroke mortality.

Authors:  George Howard
Journal:  Stroke       Date:  2013-09-12       Impact factor: 7.914

Review 2.  The future of warfarin pharmacogenetics in under-represented minority groups.

Authors:  Larisa H Cavallari; Minoli A Perera
Journal:  Future Cardiol       Date:  2012-07

Review 3.  The economic consequences of diabetes and cardiovascular disease in the United States.

Authors:  Miguel A Ariza; Varsha G Vimalananda; James L Rosenzweig
Journal:  Rev Endocr Metab Disord       Date:  2010-03       Impact factor: 6.514

Review 4.  Stroke risk in women: the role of menopause and hormone therapy.

Authors:  Lynda Lisabeth; Cheryl Bushnell
Journal:  Lancet Neurol       Date:  2012-01       Impact factor: 44.182

5.  Does socioeconomic status or acculturation modify the association between ethnicity and hypertension treatment before stroke?

Authors:  Deborah A Levine; Lewis B Morgenstern; Kenneth M Langa; Lesli E Skolarus; Melinda A Smith; Lynda D Lisabeth
Journal:  Stroke       Date:  2013-09-17       Impact factor: 7.914

6.  Challenge and Yield of Enrolling Racially and Ethnically Diverse Patient Populations in Low Event Rate Clinical Trials.

Authors:  Alice J Sheffet; George Howard; Albert Sam; Zafar Jamil; Fred Weaver; David Chiu; Jenifer H Voeks; Virginia J Howard; Susan E Hughes; Linda Flaxman; Mary E Longbottom; Thomas G Brott
Journal:  Stroke       Date:  2017-11-30       Impact factor: 7.914

7.  Risk of major bleeding by ethnicity and socioeconomic deprivation among 488,107 people in primary care: a cohort study.

Authors:  Wai Chung Tse; Corina Grey; Matire Harwood; Rod Jackson; Andrew Kerr; Suneela Mehta; Katrina Poppe; Romana Pylypchuk; Sue Wells; Vanessa Selak
Journal:  BMC Cardiovasc Disord       Date:  2021-04-23       Impact factor: 2.298

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.