Literature DB >> 18497566

Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines.

Xavier Graña1.   

Abstract

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Year:  2008        PMID： 18497566     DOI： 10.4161/cbt.7.6.6298

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN： 1538-4047            Impact factor:   4.742


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  9 in total

Review 1.  PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates.

Authors:  Alison Kurimchak; Xavier Graña
Journal:  Gene       Date:  2012-02-22       Impact factor: 3.688

2.  B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation.

Authors:  Girish Jayadeva; Alison Kurimchak; Judit Garriga; Elena Sotillo; Anthony J Davis; Dale S Haines; Marc Mumby; Xavier Graña
Journal:  J Biol Chem       Date:  2010-07-27       Impact factor: 5.157

3.  Langerhans cell protein 1 (LCP1) binds to PNUTS in the nucleus: implications for this complex in transcriptional regulation.

Authors:  Shin Jeong Lee; Jun Ki Lee; Yong Sun Maeng; Young Myeong Kim; Young Guen Kwon
Journal:  Exp Mol Med       Date:  2009-03-31       Impact factor: 8.718

4.  Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.

Authors:  Alison Kurimchak; Dale S Haines; Judit Garriga; Shufang Wu; Francesco De Luca; Michael J Sweredoski; Raymond J Deshaies; Sonja Hess; Xavier Graña
Journal:  Mol Cell Biol       Date:  2013-06-17       Impact factor: 4.272

5.  Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.

Authors:  Meng S Choy; Martina Hieke; Ganesan Senthil Kumar; Greyson R Lewis; Kristofer R Gonzalez-DeWhitt; Rene P Kessler; Benjamin J Stein; Manuel Hessenberger; Angus C Nairn; Wolfgang Peti; Rebecca Page
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-03       Impact factor: 11.205

6.  PNUTS functions as a proto-oncogene by sequestering PTEN.

Authors:  Sridhar Kavela; Swapnil R Shinde; Raman Ratheesh; Kotapalli Viswakalyan; Murali D Bashyam; Swarnalata Gowrishankar; Mohana Vamsy; Sujit Pattnaik; Subramanyeshwar Rao; Regulagadda A Sastry; Mukta Srinivasulu; Junjie Chen; Subbareddy Maddika
Journal:  Cancer Res       Date:  2012-11-01       Impact factor: 12.701

7.  GENE EXPRESSION PROFILING OF HUMAN LIVER CARCINOMA (HepG2) CELLS EXPOSED TO THE MARINE TOXIN OKADAIC ACID.

Authors:  Lynne A Fieber; Justin B Greer; Fujiang Guo; Douglas C Crawford; Kathleen S Rein
Journal:  Toxicol Environ Chem       Date:  2012-10-10       Impact factor: 1.437

8.  PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.

Authors:  Anita Ciurciu; Louise Duncalf; Vincent Jonchere; Nick Lansdale; Olga Vasieva; Peter Glenday; Andreii Rudenko; Emese Vissi; Neville Cobbe; Luke Alphey; Daimark Bennett
Journal:  PLoS Genet       Date:  2013-10-31       Impact factor: 5.917

9.  PNUTS mediates ionizing radiation-induced CNE-2 nasopharyngeal carcinoma cell migration, invasion, and epithelial-mesenchymal transition via the PI3K/AKT signaling pathway.

Authors:  Dan Yu; Xiang An; Wanlin Fan; Xin Wang; Yuxing He; Bing Li
Journal:  Onco Targets Ther       Date:  2019-02-15       Impact factor: 4.147
  9 in total

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